Retarding effect of dietary fibers from bamboo shoot (Phyllostachys edulis) in hyperlipidemic rats induced by a high-fat diet

文献类型： 外文期刊

第一作者： Li, Qi

作者： Li, Qi;Fang, Xiangjun;Chen, Hangjun;Han, Yanchao;Liu, Ruiling;Wu, Weijie;Gao, Haiyan;Fang, Xiangjun;Chen, Hangjun;Han, Yanchao;Liu, Ruiling;Wu, Weijie;Gao, Haiyan;Fang, Xiangjun;Chen, Hangjun;Han, Yanchao;Liu, Ruiling;Wu, Weijie;Gao, Haiyan;Fang, Xiangjun;Chen, Hangjun;Han, Yanchao;Liu, Ruiling;Wu, Weijie;Gao, Haiyan

作者机构：

期刊名称：FOOD & FUNCTION （ 影响因子：4.171； 五年影响因子：4.364 ）

ISSN： 2042-6496

年卷期： 2021 年 12 卷 10 期

页码：

收录情况： SCI

摘要： The effects of the administration of bamboo shoot (Phyllostachys edulis) dietary fiber (BSDF) on high-fat diet (HDF) induced hyperlipidemia were studied with SD rat models. The results indicated that the body weight of rats and the mass of their adipose tissue were significantly (P < 0.05) decreased after the combination treatment of soluble dietary fiber (SDF) and insoluble dietary fiber (IDF). The levels of total cholesterol, triglyceride, and low-density lipoprotein cholesterol were significantly (P < 0.05) decreased by 30.20%, 53.28% and 35.63%, respectively, compared to those of the model group. The levels of serum alanine aminotransferase, aspartate aminotransferase, leptin, and insulin-like growth factor-1 of the SDF + IDF group were also significantly lower than those of the HDF model group (P < 0.05). Additionally, the perirenal fat percentage and body fat percentage in the SDF + IDF group were reduced by 31.61% and 25.09%, respectively. IDF exhibited better hypolipidemic ability than SDF in HFD induced rats at the same dose, while SDF and IDF showed a synergistic hyperlipidemia prevention effect. The mRNA expression levels of lipid synthesis genes SREBP-1c and FAS were significantly down-regulated by SDF + IDF treatment (P < 0.05). These results suggested that BSDF composed of IDF and SDF, with potential hypolipidemic effects, could be used in the production of health-beneficial food.

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