Application of High-Throughput Sequencing on the Chinese Herbal Medicine for the Data-Mining of the Bioactive Compounds
文献类型： 外文期刊
第一作者： Liu, Xiaoyan
作者： Liu, Xiaoyan;Liu, Yi;Liu, Junlin;Zhang, Hantao;Qiao, Sen;Tang, Min;Gong, Xun;Liu, Yi;Li, Gang
作者机构：
关键词： Chinese herbal medicine; high-throughput sequencing technologies; genome assembly; bioactive compounds; functional genes
期刊名称：FRONTIERS IN PLANT SCIENCE （ 影响因子：6.627； 五年影响因子：7.255 ）
ISSN： 1664-462X
年卷期： 2022 年 13 卷
页码：
收录情况： SCI
摘要： The Chinese Herbal Medicine (CHM) has been used worldwide in clinic to treat the vast majority of human diseases, and the healing effect is remarkable. However, the functional components and the corresponding pharmacological mechanism of the herbs are unclear. As one of the main means, the high-throughput sequencing (HTS) technologies have been employed to discover and parse the active ingredients of CHM. Moreover, a tremendous amount of effort is made to uncover the pharmacodynamic genes associated with the synthesis of active substances. Here, based on the genome-assembly and the downstream bioinformatics analysis, we present a comprehensive summary of the application of HTS on CHM for the synthesis pathways of active ingredients from two aspects: active ingredient properties and disease classification, which are important for pharmacological, herb molecular breeding, and synthetic biology studies.
分类号：
- 相关文献
作者其他论文 更多>>
-
The Biosynthesis of Astaxanthin Esters in Schizochytrium sp. is Mediated by a Bifunctional Diacylglycerol Acyltransferase
作者：Liu, Peng-Yang;Wu, Jun-Jie;Li, Gang;Lin, Chu-Bin;Jiang, Shan;Liu, Shuang;Wan, Xia;Lin, Chu-Bin;Liu, Shuang;Wan, Xia
关键词：astaxanthin ester; docosahexaenoic acid; lipiddroplet; acyltransferase
-
Highly stable and antifungal properties on the oilseed rape of Cu3(MoO4)2(OH)2 nanoflakes prepared by simple aqueous precipitation
作者：Zhao, Xu;Liu, Yi;Li, Shaozhen;Xu, Lisha;Mei, Yunjun;Chen, Luocheng;Zheng, Anqi;Yin, Kuibo;Xiao, Xiaolu;Sun, Xuecheng;Zhang, Yifu
关键词：
-
Structurally diverse oxygen-containing aromatic compounds with anti-inflammatory activity from Aspergillus sp. LY-1-2
作者：Wang, Chu-Qiao;Ji, Fei-Xiang;Feng, Dan;Peng, Xiao-Ping;Lou, Hong-Xiang;Li, Gang;Pan, Jinzhi;Luo, Qian;Yuan, Shuang-Zhi;Lou, Hong-Xiang;Yuan, Chao
关键词：Endophytic fungus; Aspergillus; aromatic compounds; isocoumarins; anti-inflammatory
-
Influence of the intensive mariculture on coastal sedimentary organic matter: Insight from size-fractionated particles
作者：Sui, Juanjuan;Yang, Xiaofei;Deng, Chunmei;Zhang, Jihong;Wu, Wenguang;Liu, Yi;Sui, Juanjuan;Yang, Xiaofei;Deng, Chunmei;Zhang, Jihong
关键词：Sanggou Bay; Stable carbon isotope; Stable nitrogen isotope; Mariculture; Organic matter; Water elutriation; Particle size
-
Genomic and Comparative Transcriptomic Analyses Reveal Key Genes Associated with the Biosynthesis Regulation of Okaramine B in Penicillium daleae NBP-49626
作者：Wang, Yueying;Chen, Ling;Fang, Wei;Zeng, Zhen;Wu, Zhaoyuan;Liu, Fang;Liu, Xiaoyan;Gong, Yan;Zhu, Lei;Wang, Kaimei
关键词：Okaramine B; yield improvement; Penicillium daleae; complete genome; transcriptome; novel regulators; tryptophan metabolism
-
Ancient bayberry increased stress resistance by enriching tissue-specific microbiome and metabolites
作者：Li, Gang;Ren, Haiying;Qi, Xingjiang;Han, Hao;Ding, Xiangyang;Sun, Li;Wang, Zhenshuo;Wang, Qi;Hafeez, Rahila;Li, Bin
关键词：
-
The Bombyx mori G protein β subunit 1 ( BmGN fi 1 ) gene inhibits BmNPV infection
作者：Yu, Linyuan;Ling, Chenyu;Li, Yizhu;Guo, Huiduo;Xu, Anying;Qian, Heying;Li, Gang;Guo, Huiduo;Xu, Anying;Qian, Heying;Li, Gang
关键词：Bombyx mori; BmNPV; GNfi1; Apoptosis; PI3K-AKT
