Limonoids and triterpenoids from the stems of Chukrasia tabularis A. Juss.

文献类型: 外文期刊

第一作者: Wang, Yancui

作者: Wang, Yancui;Wang, Hao;Mei, Wenli;Kong, Fandong;Zhao, Youxing;Dai, Haofu;Wang, Yancui;Wang, Hao;Mei, Wenli;Dai, Haofu;Liu, Shoubai

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关键词: Chukrasia tabularis A. Juss.; Meliaceae; Limonoid; Triterpenoid; Acetylcholinesterase inhibitory activity

期刊名称:PHYTOCHEMISTRY LETTERS ( 影响因子:1.679; 五年影响因子:1.861 )

ISSN: 1874-3900

年卷期: 2019 年 33 卷

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收录情况: SCI

摘要: Three new limonoids named chuktabrin L (1), meliasenin Y (2), 11a-acetoxy-20,21,22,23-tetrahydro-23-oxoazadirone (3) and one new triterpenoid, named hispidol C (4), together with one known compound hispidol B (5) were isolated from the stems of Chukrasia tabularis A. Juss. Chuktabrin L (1) was a D-ring-opened 16-norphragmalin featuring a unique C-16 degraded polycyclic skeleton. Structures were elucidated by spectroscopic techniques of IR, HRESIMS and NMR. Compounds 1-5 were evaluated for acetylcholinesterase (AChE) inhibitory activity in vitro, however turned out inactive.

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