文献类型： 外文期刊
第一作者： Cao, Xue
作者： Cao, Xue;Yang, Li;Dai, Hao-Fu;Wei, Yan-Mei;Huang, Sheng-Zhuo;Wang, Hao;Cai, Cai-Hong;Mei, Wen-Li;Chen, Hui-Qin;Cao, Xue;Yang, Li;Dai, Hao-Fu;Wei, Yan-Mei;Huang, Sheng-Zhuo;Wang, Hao;Cai, Cai-Hong;Mei, Wen-Li;Chen, Hui-Qin;Cao, Xue;Wang, Ling
作者机构：
关键词： Dendrobium nobile Lindl; alpha-Glucosidase; Lignan; Fluorenone
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）
ISSN： 1874-3900
年卷期： 2021 年 44 卷
页码：
收录情况： SCI
摘要： Two new compounds, dendronobilate (1) and 4-O-demethyl-nobilone (2), together with one known fluorenone were isolated from the aerial parts of Dendrobium nobile Lindl. Their structures were characterized by detailed analysis of 1D and 2D NMR spectra, HRESIMS and ECD spectra. Compounds 1-3 showed significant alpha-glucosidase inhibitory activity with IC50 values of 27.46 +/- 3.14, 4.52 +/- 0.33, and 10.78 +/- 2.05 mu M, respectively, which were superior to the acarbose (745.9 +/- 3.3 mu M). The binding interactions of 1 and 2 with alpha-glucosidase were investigated using molecular docking simulations. In addition, compound 2 exhibited potent inhibitory effect on NO production in LPS activated RAW264.7 cells with the IC50 value of 35.40 +/- 1.77 mu M without cytotoxicity observed.
分类号：
- 相关文献
作者其他论文 更多>>
-
Polysaccharides from Astragalus membranaceus Bunge alleviate LPS-induced neuroinflammation in mice by modulating microbe-metabolite-brain axis and MAPK/NF-κB signaling pathway
作者：Liu, Dongyuan;Hou, Ziming;Wang, Hao;Zhu, Yuying;Li, Qiangqiang
关键词：Astragalus membranaceus Bunge; polysaccharides; Anti-neuroinflammation; Microbe-metabolite-brain axis
-
A collaborative scheduling and planning method for multiple machines in harvesting and transportation operations-Part I: Harvester task allocation and sequence optimization
作者：Wang, Ning;Li, Shunda;Han, Yuxiao;Zhang, Man;Li, Han;Wang, Ning;Xiao, Jianxing;Wang, Tianhai;Zhang, Man;Wang, Hao;Wang, Hao
关键词：Agricultural machine; Collaborative scheduling; Scheduling model; Electronic map; Path planning
-
Monitoring the insecticide susceptibility of a newly introduced invasive species, Tuta absoluta (Meyrick), in China
作者：Zhang, Yi-bo;Li, Han;Tian, Xiao-cao;Wang, Hao;Geng, Li-li;Zhang, Jie;Liu, Wan-xue;Wan, Fang-hao;Zhang, Gui-fen;Han, Peng;Tian, Xiao-cao;Guedes, Raul-Narciso;Nicolas, Desneux
关键词：C hemical control; Leaf miner; Diamide; Spinosyn; Bacillus thuringiensis
-
Bacterial cellulose and photothermal material from biomass-based zero-waste biorefinery functionalized chitosan film for sustainable active food packaging
作者：Yang, Li;Sheng, Wenyang;Yang, Yichen;He, Kaiwen;Jiang, Guangyang;Tian, Yongqiang;Yang, Li;Sheng, Wenyang;Yang, Yichen;He, Kaiwen;Jiang, Guangyang;Tian, Yongqiang;Yang, Ying
关键词：Zero-waste biorefining; Bacterial cellulose; Photothermal material; Chitosan; Antibacterial activity; Distillers' grains
-
New Isocoumarins from an Endophytic Fungal Strain Diaporthe arengae M2 and their Antibacterial Activities
作者：Liu, De-Sui;Ma, Qing-Yun;Yang, Li;Xie, Qing-Yi;Dai, Hao-Fu;Zhao, You-Xing;Liu, De-Sui;Ma, Qing-Yun;Yang, Li;Xie, Qing-Yi;Dai, Hao-Fu;Zhao, You-Xing;Liu, De-Sui;Zhang, Jun-Feng;Wu, You-Gen
关键词：Endophytic fungi;
Diaporthe sp.; Isocoumarin derivatives; Antibacterial activity -
Identification of stay-green candidate gene TaTRNH1-3B and development of molecular markers related to chlorophyll content and yield in wheat (Triticum aestivum L.)
作者：Jin, Xiu-Juan;Yan, Xue;Guo, Feng;Wang, Ling;Lu, Juan;Tang, Xiao-Sha;Hao, Hui-Fang;Islam, Md Ashraful;Li, Ning;Yang, Jin-Wen;Sun, Dai-Zhen;Cao, Ya-Ping;Jing, Rui-Lian
关键词：Wheat; Senescence-associated co-expressed genes; Stay-green-associated differentially expressed; genes; TaTRNH1-3B; TaTRNH1-3B-Nla III-CAPS
-
Transcriptome and metabolite reveal the inhibition induced by combined heat and drought stress on the viability of silk and pollen in summer maize
作者：Li, Hongwei;Tang, Yulou;Meng, Fanzheng;Liang, Weiwei;Wang, Yongchao;Wang, Hao;Guo, Jiameng;Yang, Qinghua;Shao, Ruixin;Zhou, Wenqi;Yang, Junwei
关键词：Combined stress; Summer maize; Silk; Pollen; Viability
