文献类型： 外文期刊
第一作者： Wang, Yu
作者： Wang, Yu;Wang, Pei;Kong, Fan-Dong;Wang, Jun;Zuo, Wen-Jian;Wang, Hao;Dai, Hao-Fu;Mei, Wen-Li;Wang, Yu
作者机构：
关键词： Euphorbiaceae; Trigonostemon filipes; indole alkaloids; cytotoxicity; AChE inhibitory activity
期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.569； 五年影响因子：1.598 ）
ISSN： 1028-6020
年卷期： 2018 年 20 卷 3 期
页码：
收录情况： SCI
摘要： A phytochemical investigation of the alkaloid constituents from Trigonostemon filipes Y. T. Chang et S. L. Mo led to the isolation of two new indole alkaloids, trigonostemine G (1) and trigonostemone J (2), together with two known ones, trigonostemine A (3) and trigonostemine B (4). Their structures were determined by extensive spectroscopic methods. Compounds 1-4 exhibited moderate AChE inhibitory activity with inhibition ratio of 31.6, 31.7, 41.7, and 42.4%, respectively. In addition, compounds 1-2 showed weak cytotoxicity against K562 and BEL-7402 human cancer cell lines. [GRAPHICS] .
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