Three new 2-(2-phenylethyl)chromone derivatives from artificial holing agarwood of Aquilaria sinensis

文献类型: 外文期刊

第一作者: Kuang, Tong-Dong

作者: Kuang, Tong-Dong;Chen, Hui-Qin;Kong, Fan-Dong;Cai, Cai-Hong;Yang, Li;Mei, Wei-Li;Dai, Hao-Fu;Kuang, Tong-Dong;Chen, Hui-Qin;Kong, Fan-Dong;Cai, Cai-Hong;Yang, Li;Mei, Wei-Li;Dai, Hao-Fu;Kuang, Tong-Dong

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关键词: Aquilaria sinensis; Agarwood; 2-(2-Phenylethyl)chromone derivative; AChE inhibitory activity

期刊名称:PHYTOCHEMISTRY LETTERS ( 影响因子:1.679; 五年影响因子:1.861 )

ISSN: 1874-3900

年卷期: 2018 年 26 卷

页码:

收录情况: SCI

摘要: Three new 2-(2-phenylethyl)chromone derivatives (1-3) were obtained from the artificial holing agarwood originating from Aquilaria sinensis. Their structures were unambiguously deduced by detailed spectroscopic analysis and the absolute configurations were determined by ECD calculations. Compounds 1-3 displayed acetylcholinesterase (AChE) inhibitory activity with the inhibition ratios in the range of 30% 45% at a concentration of 50 mu g/ml.

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