The Genus Adonis as an Important Cardiac Folk Medicine: A Review of the Ethnobotany, Phytochemistry and Pharmacology

文献类型： 外文期刊

第一作者： Shang, Xiaofei

作者： Shang, Xiaofei;Miao, Xiaolou;Yang, Feng;Wang, Chunmei;Li, Bing;Wang, Weiwei;Pan, Hu;Zhang, Jiyu;Shang, Xiaofei;Miao, Xiaolou;Yang, Feng;Wang, Chunmei;Li, Bing;Wang, Weiwei;Pan, Hu;Zhang, Jiyu;Guo, Xiao;Zhang, Yu

作者机构：

关键词： Adonis L.; cardiac glycosides; cardiovascular activity; toxicity; resources

期刊名称：FRONTIERS IN PHARMACOLOGY （ 影响因子：5.81； 五年影响因子：6.005 ）

ISSN： 1663-9812

年卷期： 2019 年 10 卷

页码：

收录情况： SCI

摘要： The genus Adonis L. (Ranunculaceae), native to Europe and Asia, comprises 32 annual or perennial herbaceous species. Due to their cardiac-enhancing effects, Adonis spp. have long been used in European and Chinese folk medicine. These plants have been widely investigated since the late 19th century, when the cardiovascular activity of Adonis vernalis L. was noted in Europe. The present paper provides a review of the phytochemistry, biological activities and toxicology in order to highlight the future prospects of the genus. More than 120 chemical compounds have been isolated, with the most important components being cardiac glycosides as well as flavones, carotenoids, coumarins and other structural types. Plants of the genus, especially A. vernalis L. and A. amurensis Regel & Radde, their extracts and their active constituents possess broad pharmacological properties, including cardiovascular, antiangiogenic, antibacterial, antioxidant, anti-inflammatory and acaricidal activities, and exhibit both diuretic effects and effects on the central nervous system. However, most plants within the 32 species have not been comprehensively studied, and further clinical evaluation of their cardiovascular activity and toxicity should be conducted after addressing the problem of the rapidly decreasing resources. This review provides new insight into the genus and lays a solid foundation for further development of Adonis.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序