文献类型： 外文期刊
第一作者： Xia, Jing
作者： Xia, Jing;Vashisth, Manoj Kumar;Jia, Huijie;Hua, Hui;Wang, Xiao-bo;Xia, Jing;Vashisth, Manoj Kumar;Jia, Huijie;Hua, Hui;Wang, Xiao-bo;Chen, Jun;Wu, Xiao-jian;Wang, Xiao-bo
作者机构：
关键词： Marimastat; Senescence; Oxidative stress; Autophagy; mTOR
期刊名称：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS （ 影响因子：3.322； 五年影响因子：3.498 ）
ISSN： 0006-291X
年卷期： 2022 年 620 卷
页码：
收录情况： SCI
摘要： Marimastat is one of the potent inhibitors of MMP (MMPIs) with few side effects. The impact of marimastat on cellular senescence remains unexplored. Our study evaluated the marimastate effect on oxidative stress-induced cell senescence using NIH3T3 cells. Marimastate administration was found to suppress senescence-beta-galactosidase (SA-beta-gal) activity and development linked with aging. Further-more, we observed that this effect of marimastat was closely linked with the recovery of autophagy dysfunction and mTOR suppression in H2O2-treated cells. Notably, this study demonstrated the mar-imastat effect on senescence inhibition for the first time. (C) 2022 Elsevier Inc. All rights reserved.
分类号：
- 相关文献
作者其他论文 更多>>
-
Unlocking the coupling potential of built-in electric field and pulsed electroreduction for efficient nitrate to ammonia at low concentrations
作者：Wang, He;Chen, Kaiyi;Wei, Jiamin;Chen, Jun;Yang, Tinghai;Wang, He;Yan, Qun;Liu, Qiang;Yan, Qun
关键词：eNO3RA; Built-in electric field; Pulsed electroreduction; Low nitrate concentration; Sustainable nitrogen recycling
-
Somatic embryogenetic receptor kinase TaSERL2 regulates heat stress tolerance in wheat by influencing TaBZR2 protein stability and transcriptional activity
作者：Hao, Xiang-Yang;Fu, Yi-Han;Xu, Wei-Gang;Hao, Xiang-Yang;Peng, Chao-Jun;Fang, Yu-Hui;Li, Yan;Dong, Hai-Bin;Xu, Wei-Gang;Hao, Xiang-Yang;Yu, Tai-Fei;Xu, Zhao-Shi;Chen, Jun;Ma, You-Zhi;Hao, Xiang-Yang;Peng, Chao-Jun;Fang, Yu-Hui;Li, Yan;Dong, Hai-Bin;Xu, Wei-Gang
关键词：common wheat; TaBZR2; heat stress; interaction identification; signal transduction; negative regulation
-
Removal of emerging organic contaminants in a subsurface wastewater infiltration system: A preliminary study of microbial mechanism
作者：Peng, Feng-Jiao;Feng, Xing-Jun;Li, Sen;Yu, Xiao-Long;Ying, Guang-Guo;Liu, You-Sheng;Peng, Feng-Jiao;Feng, Xing-Jun;Li, Sen;Yu, Xiao-Long;Ying, Guang-Guo;Liu, You-Sheng;Peng, Feng-Jiao;Feng, Xing-Jun;Li, Sen;Yu, Xiao-Long;Ying, Guang-Guo;Liu, You-Sheng;Chen, Jun;Liu, Shuang-Shuang
关键词：Emerging organic contaminants; Decentralized wastewater treatment; Subsurface wastewater infiltration system; Microbial community; Biodegradation
-
EGCG and DOX dual-drug-loaded enzyme-responsive nanovesicles boost mitochondrial-mediated ICD for improved immunotherapy
作者：Zhou, Mengxue;Wang, Ying;Zhou, Chuang;Dai, Weidong;Lv, Haipeng;Lin, Zhi;Cui, Hongchun;Yu, Jizhong;Geng, Huan;Ruan, Lifo;Chen, Jun;Ruan, Lifo;Chen, Jun;Zhao, Yanni
关键词：MMP-2 sensitive nanovesicles; EGCG; tumor fibrosis; mitochondria-targeted; cancer immunotherapy
-
Identification of candidate genes for leaf size by QTL mapping and transcriptome sequencing in Brassica napus L
作者：Cheng, Fengjie;Peng, Aoyi;Wei, Wenliang;Wang, Yuwen;Li, Shuyu;Zheng, Xiaoxiao;Xiong, Jie;Ding, Ge;Zhang, Bingchao;Song, Laiqiang;Chen, Lunlin;Chen, Jun;Zhai, Wen
关键词：Leaf width; Leaf length; Leaf area; QTL mapping; Transcriptome sequencing;
Brassica napus L -
Engineering a Tumor-Acidity-Responsive PEG-Sheddable Nanoassembly for Combating Drug Resistance
作者：Xie, Jin;Xie, Jin;Ouyang, Jun;Xie, Jin;Zhou, Mengxue;Ren, Hongyu;Dou, Rui;Zhang, Jiayu;Hu, Yi;Chen, Jun;Xie, Jin;Zhou, Mengxue;Ren, Hongyu;Dou, Rui;Zhang, Jiayu;Hu, Yi;Chen, Jun;Zhou, Mengxue;Hu, Yi
关键词：core-crosslinked micellar nanoassembly; co-delivery; drug resistance; nanomedicine; tumor-acidity-responsive
-
Synthesis of churros-like V2Se9 nanostructures for ultrasensitive electrochemical detection of oxalic acid in urine with portable point-of-care diagnostic devices
作者：Shi, Peizheng;Xu, Lixin;Shi, Peizheng;Ye, Chen;Sun, Zhuang;Sun, Kaiqiang;Zhao, Ningbin;Ye, Chen;Cai, Tao;Nishimura, Kazuhito;Jiang, Nan;Ye, Chen;Cai, Tao;Nishimura, Kazuhito;Jiang, Nan;Lin, Cheng-Te;Pourfakhr, Mahan;Chen, Jun;Tsai, Hsu-Sheng;Wu, Lidong;Wu, Wenqi;Wu, Wenqi;Yu, Jiancheng;Yu, Jiancheng;Yu, Jiancheng;Fu, Li
关键词：Electrochemical biosensors; Oxalic acid; Point-of-care testing; Biomonitoring
