Synthesis and Insecticidal Activities of Novel Spin-Labeled Derivatives of Camptothecin

文献类型： 外文期刊

第一作者： Liu, Ying-Qian

作者： Liu, Ying-Qian;Dai, Wei;Tian, Jing;Zhou, Xing-Wen;Kou, Liang;Zhao, Yong-Long;Li, Wen-Qun;Li, Lin-Hai;Li, Hong-Yu;Yang, Liu;Feng, Gang

作者机构：

期刊名称：HETEROATOM CHEMISTRY （ 影响因子：1.366； 五年影响因子：1.162 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Continuing our search for natural product based compounds for the control of Brontispa longissima larvae, eight spin-labeled camptothecin derivatives 7a-h and the intermediate 2 were first tested for their insecticidal activities against fifth-instar larvae of Brontispa longissima. Among all the tested compounds, especially compounds 7a and 2 showed promising insecticidal activities with the corrected mortality rates of 69.55% and 74.07% against fifth-instar larvae of B. longissima, respectively. The different insecticidal activity ranges of these compounds indicated that the variation of the structures of L-amino acids in these compounds markedly affected the activity profiles of this compound class, and some important SAR information has been revealed from it.

分类号： O626

  • 相关文献
作者其他论文 更多>>

微信小程序