Computational identification of microRNAs and their targets in apple
文献类型: 外文期刊
第一作者: Ye, Keyong
作者: Ye, Keyong;Guo, Jianchun;Chen, Yao;Chen, Yao;Hu, Xinwen
作者机构:
关键词: Apple;MiRNA;MiRNA precursor;MiRNA target;MiRNA clusters
期刊名称:GENES & GENOMICS ( 影响因子:1.839; 五年影响因子:1.329 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: MicroRNAs (miRNAs) are small RNAs approximately 21 nucleotides in length that regulate post-transcriptional gene expression by cleaving or inhibiting the translation of target gene transcripts. Based on the conservation of miRNAs in many plant speciesand the currently available genome sequence, 154 individual conserved miRNAs have been predicted in apple (Malus domestica), and found that these miRNAs belong to 26 families. 424 miRNA:target pairs between 150 miRNAs and 235 mRNAs have been predicted in apple, and these miRNA targets are involved in development, response to biotic and abiotic stresses, and other cellular processes. From studying the miR395 and miR399 clusters in apple, it was confirmed that the expansion of miRNA gene families in apple came about via segmental duplications. The study of divergence in homologous miRNA indicates thatmiRNA/miRNA* region is more conservative than loop-containing region.
分类号: Q
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