External Application of the Volatile Oil from Blumea balsamifera May Be Safe for Liver - A Study on Its Chemical Composition and Hepatotoxicity

文献类型： 外文期刊

第一作者： Pang, Yu-Xin

作者： Pang, Yu-Xin;Fan, Zuo-Wang;Wang, Dan;Wang, Kai;Chen, Xiao-Lu;Hu, Xuan;Yu, Fu-Lai;Chen, Zhen-Xia;Pang, Yu-Xin;Fan, Zuo-Wang;Wang, Dan;Wang, Kai;Chen, Xiao-Lu;Hu, Xuan;Yu, Fu-Lai;Chen, Zhen-Xia;Fan, Zuo-Wang;Yang, Quan;Pang, Yu-Xin;Fan, Zuo-Wang;Wang, Dan;Wang, Kai;Chen, Xiao-Lu;Hu, Xuan;Yu, Fu-Lai;Chen, Zhen-Xia

作者机构：

关键词： Blumea balsamifera;Ainaxiang;Nalong;Sambong;essential oil;chemical composition;hepatotoxicity

期刊名称：MOLECULES （ 影响因子：4.411； 五年影响因子：4.587 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Ainaxiang (Blumea balsamifera), also known as Sambong, is an important ancient medicinal herb in Southeast Asia. It is rich in volatile oil, and still widely used nowadays for skin wound healing and treatment of sore throats. We analyzed the volatile oil from Blumea balsamifera (BB oil) by gas chromatography-mass spectrometry (GC-MS). Forty one components, including L-borneol, were identified. Next, the damaging effects of BB oil diluted with olive oil on liver at different concentrations (100%, 50%, 20%), were evaluated, using both normal and wounded skin. Plasma ALT, AST, ALP and TBili were assessed, along with liver histopathology. The results showed that serum levels of liver toxicity markers in the high concentration groups (100% w/v) increased compared with control groups, whereas no significant changes was observed in histopathology of liver samples. In the wound groups, treatment with BB oil resulted in a decrease in serum toxicity index, compared with normal animal groups. This study confirms the safety of short term BB oil consumption, though high BB oil doses may lead to mild liver injury and this response might be weakened in the case of cutaneous wounds. These results are expected to be helpful for guiding appropriate therapeutic use of BB oil.

分类号： O62

  • 相关文献

[1]Blumea balsamifera-A Phytochemical and Pharmacological Review. Pang, Yuxin,Wang, Dan,Chen, Xiaolu,Yu, Fulai,Fan, Zuowang,Hu, Xuan,Pang, Yuxin,Wang, Kai,Yuan, Lei,Fan, Zuowang. 2014

[2]Variations in Essential Oil Yield, Composition, and Antioxidant Activity of Different Plant Organs from Blumea balsamifera (L.) DC. at Different Growth Times. Yuan, Yuan,Huang, Mei,Pang, Yu-Xin,Yu, Fu-Lai,Chen, Zhen-Xia,Zhang, Ying-Bo,Chen, Xiao-Lu,Hu, Xuan,Huang, Mei,Pang, Yu-Xin,Yu, Fu-Lai,Chen, Zhen-Xia,Zhang, Ying-Bo,Chen, Xiao-Lu,Hu, Xuan,Chen, Ce,Liu, Li-Wei.

[3]Chemical Composition and Antimicrobial Activity of the Essential Oil from Ambrosia trifida L.. Kong, Chui Hua,Zhang, Chao Man.

[4]Chemical Variation in Essential Oil of Cymbidium sinense Flowers from Six Cultivars. Li, Jie,Zhu, Gen-fa,Wang, Zai-hua.

[5]In vitro and in vivo anti-tobacco mosaic virus activities of essential oils and individual compounds. Lu Min,Yao, Lei,Han, Zhiqiang,Xu, Yun.

[6]Effects of essential oils from Chinese indigenous aromatic plants on mycelial growth and morphogenesis of three phytopathogens. Lu, Min,Yao, Lei,Han, Zhiqiang,Xu, Yun.

[7]Effect of Soyasaponins-Rich Extract from Soybean on Acute Alcohol-Induced Hepatotoxicity in Mice. Yang, Xiushi,Ren, Guixing,Yang, Xiushi,Dong, Chuan.

[8]Activating nuclear xenobiotic receptors and triggering ER stress and hepatic cytochromes P450 systems in quails (Coturnix C-coturnix) during atrazine exposure. Du, Zheng-Hai,Qin, Lei,Lin, Jia,Xia, Jun,Zhang, Cong,Li, Xue-Nan,Li, Jin-Long,Qin, Lei,Sun, Yan-Chun,Zhang, Cong,Li, Xue-Nan,Li, Jin-Long.

[9]Comparative Proteomic Analysis Shows an Elevation of Mdh1 Associated with Hepatotoxicity Induced by Copper Nanoparticle in Rats. Dong Shu-wei,Gao Zhao-hui,Li Xia,Shen Xiao-yun,Gao Zhao-hui,Xue Hui-wen. 2014

[10]Genetic diversity of the Chinese traditional herb Blumea balsamifera (Asteraceae) based on AFLP markers. Pang, Y. X.,Zhang, Y. B.,Yu, J. B.,Zhu, M.,Chen, Y. Y.,Wang, W. Q.,Yuan, Y.. 2014

[11]NIR Rapid Assessments of Blumea balsamifera (Ai-na-xiang) in China. Yu, Fu-Lai,Huang, Mei,Wang, Dan,Zhang, Ying-Bo,Hu, Xuan,Chen, Xiao-Lu,Pang, Yu-Xin,Zhao, Na,Zhao, Na,Wu, Zhi-Sheng,Huang, Lu-Qi,Pang, Yu-Xin,Pang, Yu-Xin.

[12]Gas Chromatography-Mass Spectrometric Analysis of Nematicidal Essential Oil of Valeriana amurensis P Smirn ex Kom (Valerianaceae) Roots and its Activity against Heterodera avenae. Li, Yun Chao,Ji, Hua,Li, Hong Tao. 2015

[13]Comparison of essential oils of clove buds extracted with supercritical carbon dioxide and other three traditional extraction methods. Guan Wenqiang,Li Shufen,Yan Ruixiang,Tang Shaokun,Quan Can. 2007

[14]Comparison of the volatile compounds of crude and processed Atractylodis rhizome analyzed by GC-MS. Zhou, Jie,Guo, Lan-ping,Huang, Lu-qi,Zhou, Jie,Fang, Lei,Wang, Xiao,Zhang, Ji. 2012

[15]Comparison of composition and antifungal activity of Artemisia argyi Levl. et Vant inflorescence essential oil extracted by hydrodistillation and supercritical carbon dioxide. Guan, Wenqiang,Li, Shufen,Yan, Ruixiang,Huang, Yanfeng. 2006

[16]Comparison of Compositions and Antimicrobial Activities of Essential Oils from Chemically Stimulated Agarwood, Wild Agarwood and Healthy Aquilaria sinensis (Lour.) Gilg Trees. Chen, Huaiqiong,Yang, Yun,Xue, Jian,Wei, Jianhe,Zhang, Zheng,Chen, Hongjiang,Chen, Huaiqiong,Yang, Yun,Xue, Jian,Wei, Jianhe,Zhang, Zheng,Chen, Hongjiang,Yang, Yun,Chen, Hongjiang,Yang, Yun,Chen, Hongjiang.

[17]Essential Oil from Sweet Potato Vines, a Potential New Natural Preservative, and an Antioxidant on Sweet Potato Tubers: Assessment of the Activity and the Constitution. Yuan, Bo,Xue, Ling-wei,Zhang, Qiu-yue,Peng, Jun,Kou, Meng,Jiang, Ji-hong,Yuan, Bo,Xue, Ling-wei,Zhang, Qiu-yue,Peng, Jun,Kou, Meng,Jiang, Ji-hong,Kou, Meng,Kong, Wan-wan.

[18]Chemical composition, antimicrobial activity against Staphylococcus aureus and a pro-apoptotic effect in SGC-7901 of the essential oil from Toona sinensis (A. Juss.) Roem. leaves. Wu, Jian-Guo,Wu, Yan-Bin,Wu, Jin-Zhong,Peng, Wei,Yi, Jun,Chen, Ti-Qiang,Wong, Ka-Hing. 2014

[19]Acaricidal activities of the essential oil from Rhododendron nivale Hook. f. and its main compund, delta-cadinene against Psoroptes cuniculi. Guo, Xiao,Shang, Xiaofei,Li, Bing,Zhou, Xu Zheng,Wen, Hao,Zhang, Jiyu.

[20]GC-MS Analysis of Nematicidal Essential Oil of Mentha canadensis Aerial Parts against Heterodera avenae and Meloidogyne incognita. Ji, Hua,Li, Yun Chao,Wen, Zhi Yu,Li, Hong Tao,Ji, Hua,Li, Yun Chao,Wen, Zhi Yu,Li, Hong Tao,Li, Xiu Hua,Zhang, Hai Xin.

作者其他论文 更多>>

微信小程序