Generation and evaluation of a recombinant genotype VII Newcastle disease virus expressing VP3 protein of Goose parvovirus as a bivalent vaccine in goslings

文献类型： 外文期刊

第一作者： Wang, Jianzhong

作者： Wang, Jianzhong;Cong, Yanlong;Yin, Renfu;Ding, Zhuang;Wang, Jianzhong;Cong, Yanlong;Yin, Renfu;Ding, Zhuang;Wang, Chunfeng;Feng, Na;Yang, Songtao;Xia, Xianzhu;Xiao, Yueqiang;Wang, Wenxiu;Liu, Xiufan;Hu, Shunlin;Ding, Chan;Yu, Shengqing

作者机构：

关键词： Recombinant Newcastle disease virus;Goose parvovirus;VP3;Vectored vaccine;Attenuated

期刊名称：VIRUS RESEARCH （ 影响因子：3.303； 五年影响因子：3.445 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Newcastle disease virus (NDV) and Goose parvovirus (GPV) are considered to be two of the most important and widespread viruses infecting geese. In this study, we generated a recombinant rmNA-VP3, expressing GPV VP3 using a modified goose-origin NDV NA-1 by changing the multi-basic cleavage site motif RRQKR down arrow F of the F protein to the dibasic motif GRQGR down arrow L as that of the avirulent strain LaSota as a vaccine vector. Expression of the VP3 protein in rmNA-VP3 infected cells was detected by immunofluorescence and Western blot assay. The genetic stability was examined by serially passaging 10 times in 10-day-old embryonated SPF chicken eggs. Goslings were inoculated with rmNA-VP3 showed no apparent signs of disease and developed a strong GPV and NDV neutralizing antibodies response. This is the first study demonstrating that recombinant NDV has the potential to serve as bivalent live vaccine against Goose parvovirus and Newcastle disease virus infection in birds. (C) 2015 Elsevier B.V. All rights reserved.

分类号： R37

  • 相关文献

[1]Recombinant Newcastle disease virus expressing African swine fever virus protein 72 is safe and immunogenic in mice. Chen, Xinxin,Yang, Jifei,Ji, Yanhong,Liu, Bin,Li, Xiaoyang,Yin, Hong,Zhu, Qiyun,Yin, Hong,Okoth, Edward. 2016

[2]Label-Free Quantitative Proteomic Analysis of Differentially Expressed Membrane Proteins of Pulmonary Alveolar Macrophages Infected with Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus and Its Attenuated Strain. Qu, Zehui,Gao, Fei,Li, Liwei,Zhang, Yujiao,Jiang, Yifeng,Yu, Lingxue,Zhou, Yanjun,Zheng, Hao,Tong, Wu,Li, Guoxin,Tong, Guangzhi,Qu, Zehui,Jiang, Yifeng,Yu, Lingxue,Zhou, Yanjun,Zheng, Hao,Tong, Wu,Li, Guoxin,Tong, Guangzhi. 2017

[3]Antigenic structure analysis of VP3 of infectious bursal disease virus. Deng, Xiaoyun,Gao, Yulong,Gao, Honglei,Qi, Xiaole,Cheng, Yu,Wang, Xiaoyan,Wang, Xiaomei. 2007

[4]Kobuvirus VP3 protein restricts the IFN-beta-triggered signaling pathway by inhibiting STAT2-IRF9 and STAT2-STAT2 complex formation. Peng, Qianqian,Lan, Xi,Wang, Chen,Wang, Junyong,Zhu, Qiyun,Ren, Yujie,Yue, Ningning,Zhong, Bo,Zhong, Bo. 2017

[5]A single amino acid in the C-terminus of VP3 protein influences the replication of attenuated infectious bursal disease virus in vitro and in vivo. Wang, Yongqiang,Qi, Xiaole,Kang, Zhonghui,Yu, Fei,Qin, Liting,Gao, Honglei,Gao, Yulong,Wang, Xiaomei. 2010

[6]Recombinant lentogenic Newcastle disease virus expressing Ebola virus GP infects cells independently of exogenous trypsin and uses macropinocytosis as the major pathway for cell entry. Wen, Zhiyuan,Zhao, Bolin,Song, Kun,Hu, Xule,Chen, Weiye,Kong, Dongni,Ge, Jinying,Bu, Zhigao. 2013

[7]Recombinant Newcastle disease viral vector expressing hemagglutinin or fusion of canine distemper virus is safe and immunogenic in minks. Ge, Jinying,Wang, Xijun,Tian, Meijie,Wen, Zhiyuan,Yu, Guimei,Zhou, Weiwei,Zu, Shulong,Bu, Zhigao,Gao, Yuwei.

[8]Newcastle disease virus-vectored Nipah encephalitis vaccines induce B and T cell responses in mice and long-lasting neutralizing antibodies in pigs. Kong, Dongni,Wen, Zhiyuan,Su, Hua,Ge, Jinying,Chen, Weiye,Wang, Xijun,Wu, Chao,Chen, Hualan,Bu, Zhigao,Kong, Dongni,Wen, Zhiyuan,Su, Hua,Ge, Jinying,Chen, Weiye,Wang, Xijun,Wu, Chao,Chen, Hualan,Bu, Zhigao,Kong, Dongni,Yang, Chinglai.

[9]Genetically engineered Newcastle disease virus expressing human interferon-1 induces apoptosis in gastric adenocarcinoma cells and modulates the Th1/Th2 immune response. Bu, Xuefeng,Li, Mi,Li, Mi,Zhao, Yinghai,Liu, Sha,Wang, Mubin,Ge, Jinying,Bu, Zhigao,Yan, Yulan.

[10]Protective efficacy of a recombinant Newcastle disease virus expressing glycoprotein of vesicular stomatitis virus in mice. Zhang, Minmin,Ge, Jinying,Li, Xiaofang,Chen, Weiye,Wang, Xijun,Wen, Zhiyuan,Bu, Zhigao. 2016

[11]Identification of the interaction and interaction domains of chicken anemia virus VP2 and VP3 proteins. Sun, Fenfen,Pan, Wei,Gao, Honglei,Qi, Xiaole,Qin, Liting,Wang, Yongqiang,Gao, Yulong,Wang, Xiaomei,Sun, Fenfen,Pan, Wei. 2018

[12]Ribosomal protein L4 interacts with viral protein VP3 and regulates the replication of infectious bursal disease virus. Chen, Yuming,Lu, Zhen,Zhang, Lizhou,Gao, Li,Wang, Nian,Gao, Xiang,Wang, Yongqiang,Li, Kai,Gao, Yulong,Cui, Hongyu,Gao, Honglei,Liu, Changjun,Zhang, Yanping,Qi, Xiaole,Wang, Xiaomei,Wang, Xiaomei.

[13]Identification of a recombinant Muscovy Duck parvovirus (MDPV) in Shanghai, China. Zhu, Yumin,Zhou, Zongqing,Huang, Yu,Yu, Ruisong,Dong, Shijuan,Li, Zhen,Zhu, Yumin,Zhou, Zongqing,Huang, Yu,Yu, Ruisong,Dong, Shijuan,Li, Zhen,Zhang, Yuanshu.

[14]Novel duck parvovirus identified in Cherry Valley ducks (Anas platyrhynchos domesticus), China. Li, Chuanfeng,Li, Qi,Chen, Zongyan,Liu, Guangqing.

[15]Genetic Characterization of a Potentially Novel Goose Parvovirus Circulating in Muscovy Duck Flocks in Fujian Province, China. Wang, Shao,Cheng, Xiao-Xia,Chen, Shao-Ying,Zhu, Xiao-Li,Chen, Shi-Long,Lin, Feng-Qiang,Li, Zhao-Long,Wang, Shao,Cheng, Xiao-Xia,Chen, Shao-Ying,Chen, Shi-Long,Lin, Feng-Qiang. 2013

[16]Rapid diagnosis of goose viral infections by multiplex PCR. Chen, Zongyan,Li, Chuanfeng,Li, Guoxin,Yu, Hai,Jiang, Yifeng,Yan, Liping,Meng, Chunchun,Zhou, Yanjun,Tong, Guangzhi,Liu, Guangqing.

[17]Complete Genome Sequence of Goose Parvovirus Isolated from Anser cygnoides in China. Wan, Chun-he,Hu, Kai-hui,Wan, Chun-he,Huang, Yu,Shi, Shao-hua,Fu, Guang-hua,Cheng, Long-fei,Chen, Hong-mei,Fu, Qiu-ling,Chen, Cui-teng. 2016

[18]Evidence for natural recombination in the capsid gene VP2 of Taiwanese goose parvovirus. Wang, Shao,Cheng, Xiaoxia,Chen, Shaoying,Lin, Fengqiang,Chen, Shilong,Zhu, Xiaoli,Wang, Jingxiang,Wang, Shao,Cheng, Xiaoxia,Chen, Shaoying,Lin, Fengqiang,Chen, Shilong,Zhu, Xiaoli,Wang, Jingxiang.

[19]Expression, Purification, Characterization and Subcellular Localization of the Goose Parvovirus Rep1 Protein. Chen, Zongyan,Li, Chuanfeng,Peng, Gaojing,Liu, Guangqing. 2013

[20]Comparative genetic analysis and pathological characteristics of goose parvovirus isolated in Heilongjiang, China. Niu, Yinjie,Zhao, Lili,Liu, Baihan,Yin, Haichang,Huo, Hong,Chen, Hongyan,Liu, Baihan,Liu, Jingli,Yang, Fan. 2018

作者其他论文 更多>>

微信小程序