A novel highly pathogenic H5N8 avian influenza virus isolated from a wild duck in China

文献类型： 外文期刊

第一作者： Fan, Shengtao

作者： Fan, Shengtao;Fan, Shengtao;Fan, Shengtao;Gao, Yuwei;Xia, Xianzhu;Zhou, Lichen;Wang, Tianhou;Wu, Di;Pei, Enle;Gao, Xiaolong

作者机构：

关键词： H5N8;highly pathogenic avian influenza virus;wild duck

期刊名称：INFLUENZA AND OTHER RESPIRATORY VIRUSES （ 影响因子：4.38； 五年影响因子：4.529 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Migrating wild birds are considered natural reservoirs of influenza viruses and serve as a potential source of novel influenza strains in humans and livestock. During routine avian influenza surveillance conducted in eastern China, a novel H5N8 (SH-9) reassortant influenza virus was isolated from a mallard duck in China. blast analysis revealed that the HA, NA, PB1, PA, NP, and M segments of SH-9 were most closely related to the corresponding segments of A/duck/Jiangsu/k1203/2010 (H5N8). The SH-9 virus preferentially recognized avian-like influenza virus receptors and was highly pathogenic in mice. Our results suggest that wild birds could acquire the H5N8 virus from breeding ducks and spread the virus via migratory bird flyways.

分类号： R56

  • 相关文献

[1]Multiple adaptive amino acid substitutions increase the virulence of a wild waterfowl-origin reassortant H5N8 avian influenza virus in mice. Yu, Zhijun,Sun, Weiyang,Zhang, Xinghai,Xia, Xianzhu,Gao, Yuwei,Xia, Xianzhu,Gao, Yuwei,Cheng, Kaihui,Xia, Xianzhu,Gao, Yuwei. 2018

[2]The innate immunity of guinea pigs against highly pathogenic avian influenza virus infection. Zhang, Kun,Xu, Wei wei,Zhang, Zhaowei,Liu, Jing,Sun, Weiyang,Sang, Xiaoyu,Ren, Zhiguang,Yu, Zhijun,Li, Yuanguo,Feng, Na,Wang, Tiecheng,Wang, Hualei,Yang, Songtao,Zhao, Yongkun,Gao, Yuwei,Xia, Xianzhu,Zhang, Kun,Li, Jing,Liu, WenJun,Sun, Lijuan,Zhang, Xuemei,Jiao, Peirong,Liao, Ming,Wilker, Peter R.,Chen, Hualan. 2017

[3]Virulence of an H5N8 highly pathogenic avian influenza is enhanced by the amino acid substitutions PB2 E627K and HA A149V. Wu, Haibo,Peng, Xiuming,Liu, Fumin,Cheng, Linfang,Lu, Xiangyun,Yao, Hangping,Wu, Nanping,Lu, Rufeng,Xu, Lihua.

作者其他论文 更多>>

微信小程序