Sesquiterpenoids from Chinese Agarwood Induced by Artificial Holing

文献类型： 外文期刊

第一作者： Li, Wei

作者： Li, Wei;Liao, Ge;Dong, Wen-Hua;Kong, Fan-Dong;Wang, Pei;Wang, Hao;Mei, Wen-Li;Dai, Hao-Fu;Li, Wei;Dong, Wen-Hua;Mei, Wen-Li;Dai, Hao-Fu

作者机构：

关键词： sesquiterpenoid;Chinese agarwood induced by artificial holing;Aquilaria sinensis;AChE inhibition activity;antibacterial activity

期刊名称：MOLECULES （ 影响因子：4.411； 五年影响因子：4.587 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： Two new sesquiterpenoids, 3-oxo-7-hydroxylholosericin A (1) and 1,5;8,12-diepoxy-guaia-12-one (2), together with seven known sesquiterpenoids 3-9, were isolated from Chinese agarwood induced by artificial holing originating from Aquilaria sinensis (Lour.) Gilg. Their structures were identified by spectroscopic techniques (UV, IR, 1D and 2D NMR) and MS analyses. The absolute configuration of compound 1 was determined by comparison of its measured CD curve with that of calculated data for 1 and ent-1. The NMR data of 3 were reported in this study for the first time. Compounds 1, 2, 4-6, together with the EtOAc extract showed moderate inhibitory activities against acetylcholinesterase, and compounds 4-6, 8 exhibited antibacterial activities against Staphylococcus aureus or Ralstonia solanacearum.

分类号： O62

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