Three new sesquiterpenoids from agarwood of Aquilaria crassna

文献类型： 外文期刊

第一作者： Wang, Hong-Ni

作者： Wang, Hong-Ni;Dong, Wen-Hua;Huang, Sheng-Zhuo;Li, Wei;Kong, Fan-Dong;Wang, Hao;Wang, Jun;Mei, Wen-Li;Dai, Hao-Fu;Wang, Hong-Ni

作者机构：

关键词： Aquilaria crassna;Agarwood;Sesquiterpenoid;Acetylcholinesterase inhibition activity;Antibacterial activity

期刊名称：FITOTERAPIA （ 影响因子：2.882； 五年影响因子：3.202 ）

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年卷期：

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收录情况： SCI

摘要： Three new sesquiterpenoids (1-3), together with two known ones were isolated from the EtOAc extract of agarwood originating from Aquilaria crassna. The new compounds were elucidated on the basis of spectroscopic techniques (UV, IR, MS, 1D and 2D NMR). Compounds 1-5 were isolated from agarwood of A. crassna for the first time. In the acetylcholinesterase inhibition experiment of 2-5, compound 3 showed acetylcholinesterase inhibition activity (IR 42.9 +/- 0.6%). Compound 5 expressed antibacterial activities against Staphylococcus aureus and Ralstonia solanacearum with diameter of the inhibition zones of 12.35 +/- 0.11 mm and 16.90 +/- 0.09 mm, respectively. (C) 2016 Elsevier B.V. All rights reserved.

分类号： S759.82

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