The application of proteomics in different aspects of hepatocellular carcinoma research

文献类型: 外文期刊

第一作者: Xing, Xiaohua

作者: Xing, Xiaohua;Liang, Dong;Huang, Yao;Zeng, Yongyi;Liu, Xiaolong;Liu, Jingfeng;Liang, Dong;Xing, Xiaohua;Huang, Yao;Zeng, Yongyi;Liu, Xiaolong;Liu, Jingfeng;Huang, Yao;Zeng, Yongyi;Liu, Jingfeng;Han, Xiao

作者机构:

关键词: Hepatocellular carcinoma;Proteomics;Biomarker;Recurrence/metastasis;Precision medicine

期刊名称:JOURNAL OF PROTEOMICS ( 影响因子:4.044; 五年影响因子:4.02 )

ISSN:

年卷期:

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收录情况: SCI

摘要: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors, which is causing the second leading cancer-related death worldwide. With the significant advances of high-throughput protein analysis techniques, the proteomics offered an extremely useful and versatile analytical platform for biomedical researches. In recent years, different proteomic strategies have been widely applied in the various aspects of HCC studies, ranging from screening the early diagnostic and prognostic biomarkers to in-depth investigating the underlying molecular mechanisms. In this review, we would like to systematically summarize the current applications of proteomics in hepatocellular carcinoma study, and discuss the challenges of applying proteomics in study clinical samples, as well as discuss the possible application of proteomics in precision medicine.

分类号: Q51

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