New guaiane and acorane sesquiterpenes in high quality agarwood "Qi-Nan" from Aquilaria sinensis

文献类型： 外文期刊

第一作者： Yang, Delan

作者： Yang, Delan;Wang, Jun;Li, Wei;Dong, Wenhua;Mei, Wenli;Dai, Haofu

作者机构：

关键词： Agarwood;Aquilaria sinensis;Qi-Nan;Guaianes;Acoranes;Fagrant sesquiterpene;AChE inhibitory activities

期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： Two new guaiane sesquiterpenes (1-2), one new acorane sesquiterpene (3), along with two known sesquiterpenes (4-5) were isolated from high quality agarwood 'Qi-Nan' originating from Aquilaria sinensis. Their structures were established based on spectroscopic methods including IR, HRESIMS, 1D, and 2D NMR. Compound 1 was a guaiane sesquiterpene lactone, and compound 2 was a guaiane sesquiterpene with a 5/6/7 ring carbon skeleton. Compounds 3 and 4 were acorane-type sesquiterpenes. The two acorane sesquiterpenes (3-4) possess lasting fragrant smell at room temperature. These isolated guaiane and acorane sesquiterpenes showed acetylcholinesterase inhibitory activities in different degrees ranged from 19% to 44% at the concentration of 50 mg/mL. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.

分类号： Q946

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