A novel rosamine-based fluorescent probe for bisulfite in aqueous solution

文献类型: 外文期刊

第一作者: Zhang, Di

作者: Zhang, Di;Liu Wenya;Chen, Keke;Cheng, Junye;Zhao, Yufen;Ye, Yong;Zhao, Yufen;Ye, Yong

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期刊名称:RSC ADVANCES ( 影响因子:3.361; 五年影响因子:3.39 )

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收录情况: SCI

摘要: A new rosamine-based fluorescent probe (RosCHO)for bisulfite was obtained by one pot reaction of p-phthalaldehyde and 3-(diethylamino) phenol, which showed excellent selectivity, high sensitivity and a rapid response toward bisulfite in aqueous solution. Upon the addition of HSO3-, the aldehyde moiety in probe RosCHO formed a hydrogen sulfite-dependent adduct product, leading to fluorescence enhancement due to the different ICT process. The detection limit for bisulfite was as low as 7 x 10(-8) M, and fluorescence imaging of bisulfite in MCF-7 cells demonstrated its value to practical application in biological systems.

分类号: O6

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