Selection of affinity peptides for the purification potential of porcine circovirus type 2 (PCV2) Cap virus-like particles (VLPs)
文献类型： 外文期刊
第一作者： Zheng, Guanmin
作者： Zheng, Guanmin;Ren, Tingting;Zhang, Gaiping;Zheng, Guanmin;Lu, Qingxia;Wang, Fangyu;Jin, Qianyue;Teng, Man;Zhang, Nana;Ren, Tingting;Ding, Peiyang;Zhang, Gaiping
作者机构：
期刊名称：RSC ADVANCES （ 影响因子：3.361； 五年影响因子：3.39 ）
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收录情况： SCI
摘要： In this study, we describe the use of a M13 phage-displayed random peptide library for screening novel peptide motifs that specifically recognize recombinant PCV2 Cap protein for the first time. The peptide had a sequence of YHDCFSAGFCIG, and the binding affinity was observed in the nanomolar range. In the serum blocking test, the ELISA signal of the peptide was rapidly decreased when the concentration of the PCV2 positive serum was increased.
分类号： O6
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