Integrative analysis of circRNAs acting as ceRNAs involved in ethylene pathway in tomato

文献类型： 外文期刊

第一作者： Wang, Yunxiang

作者： Wang, Yunxiang;Wang, Qing;Gao, Lipu;Zuo, Jinhua;Zhu, Benzhong;Luo, Yunbo;Deng, Zhiping

作者机构：

期刊名称：PHYSIOLOGIA PLANTARUM （ 影响因子：4.5； 五年影响因子：4.576 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Circular RNAs (circRNAs) are a large class of non-coding endogenous RNAs that could act as competing endogenous RNAs (ceRNAs) to terminate the mRNA targets' suppression of miRNAs. To elucidate the intricate regulatory roles of circRNAs in the ethylene pathway in tomato fruit, deep sequencing and bioinformatics methods were performed. After strict screening, a total of 318 circRNAs were identified. Among these circRNAs, 282 were significantly differentially expressed among wild-type and sense-/antisense-LeERF1 transgenic tomato fruits. Besides, 1254 target genes were identified and a large amount of them were found to be involved in ethylene pathway. In addition, a sophisticated regulatory model consisting of circRNAs, target genes and ethylene was set up. Importantly, 61 circRNAs were found to be potential ceRNAs to combine with miRNAs and some of the miRNAs had been revealed to participate in the ethylene signaling pathway. This research further raised the possibility that the ethylene pathway in tomato fruit may be under the regulation of various circRNAs and provided a new perspective of the roles of circRNAs.

分类号： Q945

  • 相关文献
作者其他论文 更多>>

微信小程序