文献类型: 外文期刊
第一作者: Gao, Zeqian
作者: Gao, Zeqian;Zhu, Xueliang;Dou, Yongxi
作者机构:
关键词: miR-302/367 cluster;evolution;transcriptional regulation;cell cycle;cellular signalling;epigenetic regulation
期刊名称:OPEN BIOLOGY ( 影响因子:6.411; 五年影响因子:5.898 )
ISSN: 2046-2441
年卷期: 2015 年 5 卷 12 期
页码:
收录情况: SCI
摘要: microRNAs are a subclass of small non-coding RNAs that fine-tune the regulation of gene expression at the post-transcriptional level. The miR-302/367 cluster, generally consisting of five members, miR-367, miR-302d, miR-302a, miR-302c and miR-302b, is ubiquitously distributed in vertebrates and occupies an intragenic cluster located in the gene La-related protein 7 (LARP7). The cluster was demonstrated to play an important role in diverse biological processes, such as the pluripotency of human embryonic stem cells (hESCs), self-renewal and reprogramming. This paper provides an overviewof the mir-302/367 cluster, discusses our current understanding of the cluster's evolutionary history and transcriptional regulation and reviews the literature surrounding the cluster's roles in cell cycle regulation, epigenetic regulation and different cellular signalling pathways.
分类号:
- 相关文献
作者其他论文 更多>>
-
Comprehensive analysis of the succinylome in Vero cells infected with peste des petits ruminants virus Nigeria 75/1 vaccine strain
作者:Meng, Xuelian;Zhu, Xueliang;Wang, Xiangwei;Sun, Yuefeng;Zhang, Rui;Zhang, Zhidong
关键词:Post-translational modification; Succinylation; Protein-protein interaction; Peste Des petits ruminants virus
-
Development of a competitive ELISA using monoclonal antibodies for detecting neutralizing antibodies against Peste-des-petits-ruminants virus
作者:Hu, Linjie;Xu, Haoyue;Zhu, Xueliang;Peng, Hongjiao;Deng, Ruixue;Sun, Yuefeng;Meng, Xuelian
关键词:Peste-des-petits-ruminants virus; Haemagglutinin protein; Monoclonal antibody; Competitive ELISA
-
Class IIa histone deacetylase (HDAC) inhibitor TMP269 suppresses lumpy skin disease virus replication by regulating host lysophosphatidic acid metabolism
作者:Cheng, Pengyuan;Wang, Xiangwei;Wang, Shasha;Ren, Shanhui;Liang, Zhengji;Guo, Ke;Qu, Min;Meng, Xuelian;Dou, Yongxi;Yin, Xiangping;Sun, Yuefeng
关键词:LSDV; TMP269; lysophosphatidic acid; MEK/ERK signaling pathway; viral replication; innate immune response
-
Foot-and-Mouth Virus Capsid Protein VP1 Antagonizes Type I Interferon Signaling via Degradation of Histone Deacetylase 5
作者:Gong, Qing;Ren, Shanhui;Dou, Yongxi;Tadele, Berihun Afera;Zhou, Luoyi;Wang, Tao;Yao, Kaishen;Xu, Jian;Yin, Xiangping;Sun, Yuefeng;Hu, Tao;Zhou, Luoyi;Wang, Tao
关键词:innate immune response; FMDV infection; VP1; HDAC5; IFN-beta
-
Creation of poxvirus expressing foot-and-mouth and peste des petits ruminant disease virus proteins
作者:Zhao, Zhixun;Huang, Caiyun;Zhu, Xueliang;Qi, Zheng;Cao, Yimei;Li, Pinghua;Bao, Huifang;Sun, Pu;Bai, Xingwen;Fu, Yuanfang;Li, Kun;Zhang, Jing;Ma, Xueqing;Wang, Jian;Yuan, Hong;Li, Dong;Liu, Zaixin;Zhang, Qiang;Lu, Zengjun
关键词:Foot-and-mouth disease virus; Peste des petits ruminant disease virus; Vaccinia virus Ankara strain; Recombinant live vector vaccine
-
Quantitative analysis of acetylation in peste des petits ruminants virus-infected Vero cells
作者:Meng, Xuelian;Wang, Xiangwei;Zhu, Xueliang;Sun, Yuefeng;Zhang, Rui;Zhang, Zhidong
关键词:Acetylation; Post-translational modification; protein-protein interaction; Peste des petits ruminants virus
-
Peste des Petits Ruminants Virus Upregulates STING to Activate ATF6-Mediated Autophagy
作者:Zhang, Rui;Lin, Hanrui;You, Qing;Zhang, Zhidong;Li, Yanmin;Zhang, Zhixiong;Bai, Ling;Chen, Fei;Zhu, Xueliang
关键词:STING; RNA virus; autophagy; PPRV; MDA5; UPR; ATF6