Sterile nodular panniculitis with lung and lymph node involvement in a Siberian tiger (Panthera tigris altica)
文献类型: 外文期刊
第一作者: Hu, Shou-Ping
作者: Hu, Shou-Ping;Zhang, Zhuo;Zhang, Jiao-Er;Cai, Xue-Hui;He, Xi-Jun;Nakayama, Hiroyuki
作者机构:
关键词: lung involvement;Siberian tiger;sterile nodular panniculitis;Weber-Christian disease
期刊名称:JOURNAL OF VETERINARY MEDICAL SCIENCE ( 影响因子:1.267; 五年影响因子:1.348 )
ISSN: 0916-7250
年卷期: 2017 年 79 卷 12 期
页码:
收录情况: SCI
摘要: A 2- to 4-year-old uncastrated male Siberian tiger (Panthera tigris altica) bred in a local wild animal park presented with generalized clinical signs including abdominal pain, fever, lethargy, and anorexia, along with subcutaneous nodules along the trunk. The patient subsequently died of chronic, progressive dyspnea despite 45 days of antibiotic treatment. At necropsy, mesenteric fat inflammation and multiple subcutaneous, peritoneal, and intraabdominal nodules were observed. The lungs demonstrated congestion and heavy coagulation, and necrotic foci were observed on the cut surface. Histopathologically, the nodules were identified as granulomatous fatty tissue with numerous lymphocytes, infiltration with lipid-laden macrophages, and fibrosis. These changes were also noted in the lung. The etiology of this condition remains undetermined.
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