Foot-and-mouth disease virus carrier status in Bos grunniens yaks

文献类型： 外文期刊

第一作者： Chang, Huiyun

作者： Chang, Huiyun;Ma, Yanbin;Lin, Tong;Cong, Guozheng;Du, Junzheng;Ma, Jinling

作者机构：

关键词： FMDV;Yak;Gene mutation;Carrier status

期刊名称：VIROLOGY JOURNAL （ 影响因子：4.099； 五年影响因子：3.719 ）

ISSN： 1743-422X

年卷期： 2013 年 10 卷

页码：

收录情况： SCI

摘要： Background: The carrier status of foot-and-mouth disease virus (FMDV) is complicated, and the role of carrier animals in virus transmission is controversial. To investigate the carrier status of FMDV in animals that live in high altitude, Bos grunniens yaks were infected experimentally with FMDV O/Akesu/58. Results: All of the yaks showed clinical signs of foot-and-mouth disease (FMD). Total antibody levels against FMDV measured by liquid-phase blocking enzyme-linked immunosorbent assay (LPB-ELISA) and antibody levels against nonstructural proteins (NSP) showed dynamic changes. Three of the five yaks were indentified as carrier animals by RT-PCR method, and the OP fluids from carrier yaks can cause cytopathic effect (CPE) on BHK-21 cells. At last, five persistent infection strains were isolated. Nucleotide mutations of VP1 gene were analyzed. Conclusions: After infected with FMDV, all of the yaks showed typical clinical signs. Yaks can keep carrier status for at least 8 months. Total antibody levels against FMDV measured by LPB-ELISA and antibody levels against NSP were at high level for carrier yaks. Sequence alignment of the five isolated strains showed obvious gene and protein mutations.

分类号：

  • 相关文献

[1]Comparison of immune responses against foot-and-mouth disease virus induced by fusion proteins using the swine IgG heavy chain constant region or beta-galactosidase as a carrier of immunogenic epitopes. Li, GJ,Chen, WZ,Yan, WY,Zhao, K,Liu, MQ,Zhang, J,Fei, L,Xu, QX,Sheng, ZT,Lu, YG,Zheng, ZX.

[2]Mutation of the rice ASL2 gene encoding plastid ribosomal protein L21 causes chloroplast developmental defects and seedling death. Lin, D.,Jiang, Q.,Zheng, K.,Chen, S.,Zhou, H.,Gong, X.,Dong, Y.,Chen, S.,Zhou, H.,Teng, S.,Xu, J..

[3]Mutation in acetylcholinesterase1 associated with triazophos resistance in rice stem borer, Chilo suppressalis (Lepidoptera: Pyralidae). Jiang, Xiaojing,Jiang, Weihua,Han, Zhaojun,Qu, Mingjing,Denholm, Ian,Fang, Jichao. 2009

[4]The mutation network for the hemagglutinin gene from the novel influenza A (H1N1) virus. He YunGang,Ding GuoHui,Bian Chao,Huang Zhong,Lan Ke,Sun Bing,Wang XueCai,Li Yixue,Zhao GuoPing,Jin Li,He YunGang,Ding GuoHui,Bian Chao,Huang Zhong,Lan Ke,Sun Bing,Wang XueCai,Li Yixue,Zhao GuoPing,Jin Li,He YunGang,Ding GuoHui,Bian Chao,Huang Zhong,Lan Ke,Sun Bing,Wang XueCai,Li Yixue,Zhao GuoPing,Jin Li,He YunGang,Ding GuoHui,Bian Chao,Huang Zhong,Lan Ke,Sun Bing,Wang XueCai,Li Yixue,Zhao GuoPing,Jin Li,He YunGang,Ding GuoHui,Bian Chao,Huang Zhong,Lan Ke,Sun Bing,Wang XueCai,Li Yixue,Zhao GuoPing,Jin Li,Wang HongYan,Wang XiaoNing,Yang Zhong,Zhong Yang,Zhao GuoPing,Jin Li,Jin WeiRong,Xiong Hui,Zhao GuoPing,Jin Li,Dai JianXin,Guo YaJun,Wang Hao,Wang XiaoNing,Dai JianXin,Guo YaJun,Wang Hao,Che XiaoYan,Wu Fan,Yuan ZhenAn,Zhang Xi,Yang Zhong,Zhong Yang,Cao ZhiWei,Cao ZhiWei,Zhou XiaoNong,Zhou JiaHai,Ma ZhiYong,Tong GuangZhi,Jin WeiRong,Zhao GuoPing. 2009

[5]Short and erect rice (ser) mutant from Khao Dawk Mali 105' improves plant architecture. Yan, Wengui,Jia, Limeng,Jackson, Aaron,Pan, Xuhao,Hu, Biaolin,Zhang, Qijun,Jia, Limeng,Jia, Limeng,Pan, Xuhao,Yan, Zongbu,Deren, Christopher,Pan, Xuhao,Huang, Bihu.

[6]Effects of high pressure treatment and temperature on lipid oxidation and fatty acid composition of yak (Poephagus grunniens) body fat. Wang, Qiang,Zhao, Xin,Ren, Yanrong,Wang, Qiang,Chang, Haijun,Wu, Hongbin,Fan, Enguo. 2013

[7]The Breed and Sex Effect on the Carcass Size Performance and Meat Quality of Yak in Different Muscles. Zhang, Li,Yu, Qunli,Wang, Li,Zhou, Yuchun,Li, Yongpeng,Sun, Baozhong,Xie, Peng,Li, Haipeng,Huang, Caixia,Liu, Xuan,Ji, Qiumei. 2016

[8]Effect of urea multinutritional molasses block supplementation on liveweight change of yak calves and productive and reproductive performances of yak cows. Dong, SK,Long, RJ,Kang, MY,Pu, XP,Guo, YJ. 2003

[9]Seroprevalence and Risk Factors of Fascioliasis in Yaks, Bos grunniens, from Three Counties of Gansu Province, China. Zhang, Xiao-Xuan,Ma, Jian-Gang,Zheng, Wen-Bin,Zhao, Quan,Zhang, Xiao-Xuan,Feng, Sheng-Yong,Ma, Jian-Gang,Zheng, Wen-Bin,Yin, Ming-Yang,Qin, Si-Yuan,Zhou, Dong-Hui,Zhu, Xing-Quan. 2017

[10]Genetic variation in the kappa-casein gene (CSN3) of Chinese yak (Bos grunniens) and phylogenetic analysis of CSN3 sequences in the genus Bos. Prinzenberg, E. -M.,Erhardt, G.,Jianlin, H.,Jianlin, H.. 2008

[11]Molecular and serological evidence for Anaplasma infection in yaks. Ma, Miling,Liu, Zhijie,Guan, Guiquan,Li, Youquan,Luo, Jianxun,Yin, Hong.

[12]Comparative Proteomic Analysis of Yak Follicular Fluid during Estrus. Guo, Xian,Pei, Jie,Ding, Xuezhi,Chu, Min,Bao, Pengjia,Wu, Xiaoyun,Liang, Chunnian,Yan, Ping.

[13]PPAR alpha signal pathway gene expression is associated with fatty acid content in yak and cattle longissimus dorsi muscle. Qin, W.,Liang, C. N.,Guo, X.,Chu, M.,Pei, J.,Bao, P. J.,Wu, X. Y.,Li, T. K.,Yan, P.. 2015

[14]Novel SNP of EPAS1 gene associated with higher hemoglobin concentration revealed the hypoxia adaptation of yak (Bos grunniens). Wu Xiao-yun,Ding Xue-zhi,Chu Min,Guo Xian,Bao Peng-jia,Liang Chun-nian,Yan Ping. 2015

[15]Molecular investigation of bovine viral diarrhea virus infection in yaks (Bos gruniens) from Qinghai, China. Gong, Xiaowei,Zheng, Fuying,Chen, Qiwei,Li, Zhaocai,Cao, Xiaoan,Yin, Hong,Zhou, Jizhang,Cai, Xuepeng. 2014

[16]Efficiency of in vitro embryo production of yak (Bos grunniens) cultured in different maturation and culture conditions. Guo, Xian,Ding, Xuezhi,Pei, Jie,Bao, Pengjia,Liang, Chunnian,Chu, Min,Yan, Ping,Guo, Xian,Ding, Xuezhi,Pei, Jie,Bao, Pengjia,Liang, Chunnian,Chu, Min,Yan, Ping. 2012

[17]Association between single-nucleotide polymorphisms of fatty acid synthase gene and meat quality traits in Datong Yak (Bos grunniens). Chu, M.,Wu, X. Y.,Guo, X.,Pei, J.,Liang, C. N.,Ding, X. Z.,Bao, P. J.,Yan, P.,Chu, M.,Wu, X. Y.,Guo, X.,Pei, J.,Liang, C. N.,Ding, X. Z.,Bao, P. J.,Yan, P.,Jiao, F.,Fang, H. T.. 2015

[18]Comparative proteomics of milk fat globule membrane in different species reveals variations in lactation and nutrition. Lu, Jing,Zhang, Weiqing,Liu, Lu,Pang, Xiaoyang,Zhang, Shuwen,Lv, Jiaping,Wang, Xinyu,Wang, Xinyu.

[19]Expression profiles of growth hormone receptor and insulin-like growth factor I in cattle and yak tissues revealed by quantitative real-time PCR. Pei, Jie,Lang, Xia,Guo, Xian,Bao, Pengjia,Liang, Chunnian,Chu, Min,Feng, Ruilin,Yan, Ping,Pei, Jie,Lang, Xia,Guo, Xian,Bao, Pengjia,Liang, Chunnian,Chu, Min,Yan, Ping. 2013

[20]Conserved Exon 2 but a Highly Polymorphic 5 '-UTR of Tyrosinase Gene in Tianzhu White Yak (Bos grunniens). Zhang, H.,Han, J. L.,Zhang, H.,Luo, Y. Z.,An, T. W.,He, J. W.,Han, J. L.. 2012

作者其他论文 更多>>

微信小程序