The circulation of unique reassortment strains of infectious bursal disease virus in Pakistan

文献类型: 外文期刊

第一作者: Hussain, Altaf

作者: Hussain, Altaf;Wu Tian-tian;Fan Lin-jin;Wang Yu-long;Nan, Jiang;Li, Gao;Kai, Li;Gao Yu-long;Liu Chang-jun;Cui Hong-yu;Qing, Pan;Zhang Yan Ping;Wang Xiao-mei;Qi Xiao-le;Hussain, Altaf;Wu Tian-tian;Fan Lin-jin;Wang Yu-long;Nan, Jiang;Li, Gao;Kai, Li;Gao Yu-long;Cui Hong-yu;Wang Xiao-mei;Qi Xiao-le;Wang Xiao-mei;Muhammad, Farooq Khalid;Aslam, Asim;Muti-Ur-Rehman, Khan;Arshad, Muhammad Imran;Abdullah, Hafiz Muhammad

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关键词: infectious bursal disease virus; circulating strains; reassortant; Pakistan

期刊名称:JOURNAL OF INTEGRATIVE AGRICULTURE ( 影响因子:2.848; 五年影响因子:2.979 )

ISSN: 2095-3119

年卷期: 2020 年 19 卷 7 期

页码:

收录情况: SCI

摘要: Infectious bursal disease (IBD), caused by IBD virus (IBDV), is one of the most devastating and immunosuppressive diseases of the poultry and has been a constraint on the sustainable poultry production around the globe including Pakistan. While the disease is threatening the poultry industry, the nature of predominant strains of IBDV in Pakistan remained ill-defined. In this study, an epidemiology survey was conducted in the main chicken-farming regions of Pakistan. The batch of Pakistan IBDVs genes simultaneously covering both VP1 and VP2 were amplified, sequenced, and analyzed. The unique segment-reassortant IBDVs (vv-A/Uniq-B), carrying segment A from vvIBDV and segment B from one unique ancestor, were identified as one important type of circulating strains in Pakistan. The data also discovered the characteristic molecular features of Pakistan IBDVs, which will contribute to scientific vaccine selection and effective prevention of the disease.

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