New 2-(2-Phenylethyl)chromone derivatives from agarwood originating from Aquilaria sinensis

文献类型: 外文期刊

第一作者: Li, Jun-Tao

作者: Li, Jun-Tao;Kuang, Tong-Dong;Chen, Hui-Qin;Yang, Li;Wang, Hao;Cai, Cai-Hong;Mei, Wen-Li;Dai, Hao-Fu;Liu, Shou-Bai

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关键词: Agarwood; Aquilaria sinensis; 2-(2-phenylethyl)chromone; ECD calculation

期刊名称:JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH ( 影响因子:1.61; 五年影响因子:1.591 )

ISSN: 1028-6020

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收录情况: SCI

摘要: Two new dimeric 2-(2-phenylethyl)chromones, aquilasinenones L and M (1 and 2), and one new monomer analogue, 5S, 6 R, 7S, 8 R-tetrahydroxy-[2-(3-methoxy-4-hydroxyphenyl)ethyl]- 5,6,7,8-tetrahydrochromone (3), together with two known compounds, were isolated from the artificial agarwood originating from Aquilaria sinensis. Compound 1 was the first structure found with C8-O-C4"' linkage among 2-(2-phenylethyl)chromone dimers. Their structures were unambiguously elucidated based on 1 D and 2 D NMR spectroscopy, as well as by comparison with the literature. The absolute configuration was determined by ECD calculation. None of the compounds exhibited acetylcholinesterase inhibitory activity.

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