New Xanthone from the Pericarp of Garcinia mangostana

文献类型： 外文期刊

第一作者： Fu, Manqin

作者： Fu, Manqin;Xu, Yujuan;Wu, Jijun;Chen, Yulong;Yu, Yuanshan;Xiao, Gengsheng;Qiu, Samuel X.

作者机构：

关键词： Garcinia mangostana;Xanthone;Cytotoxicity

期刊名称：NATURAL PRODUCT COMMUNICATIONS （ 影响因子：0.986； 五年影响因子：1.068 ）

ISSN： 1934-578X

年卷期： 2013 年 8 卷 12 期

页码：

收录情况： SCI

摘要： A new prenylxanthone, garcimangostanol (1), was isolated from the EtOAc-soluble partition of the ethanol extract of the pericarp of Garcinia mangostana L., along with three known compounds, namely 8-deoxygartanin (2), 1-isomangostin (3), and garcinone C (4). The structure of compound 1 was elucidated on the basis of its 1D, 2D NMR and MS data. Compounds 1-4 exhibited either significant or moderate cytotoxicity against MCF-7, A549, Hep-G2 and CNE human cancer cell lines in vitro with IC50 values from 4.0 +/- 0.3 to 23.6 +/- 1.5 mu M by MU colorimetric assay.

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