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Three new flavanoids from artificially induced dragon's blood of Dracaena cambodiana

文献类型：外文期刊

第一作者： Li, Fei-Xiang

作者： Li, Fei-Xiang;Wang, Hui;Gai, Cui-Juan;Chen, Hui-Qin;Li, Wei;Mei, Wen-Li;Dai, Hao-Fu

作者机构：

关键词： Artificially induced dragon's blood;flavanoids;Dracaena cambodiana;cytotoxicity;AChE

期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （影响因子：1.569；五年影响因子：1.598 ）

ISSN： 1028-6020

年卷期： 2018 年 20 卷 1 期

页码：

收录情况： SCI

摘要： Three new flavanoids, (2R)-7,4'-dihydroxy-8-methylflavan (1), (2R)-7,4'-dihydroxy-6-methylflavan (2), and (3R)-7,3',4'-trihydroxyhomoisoflavan (3), together with seven known compounds (4-10), were isolated from artificially induced dragon's blood of Dracaena cambodiana, and their structures were determined based on HR-ESI-MS and extensive spectroscopic techniques (UV, IR, 1D-, and 2D-NMR). Compound 2 exhibited weak cytotoxicity against BEL-7402 cells line with the IC50 value of 39.2 mu M. In addition, compound 3 showed significant acetylcholinesterase (AChE) inhibitory activity. GRAPHICS

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