Metabolites with Insecticidal Activity from Aspergillus fumigatus JRJ111048 Isolated from Mangrove Plant Acrostichum specioum Endemic to Hainan Island

文献类型： 外文期刊

第一作者： Guo, Zhikai

作者： Guo, Zhikai;Gai, Cuijuan;Cai, Caihong;Chen, Liangliang;Liu, Shoubai;Zeng, Yanbo;Yuan, Jingzhe;Mei, Wenli;Dai, Haofu;Guo, Zhikai;Gai, Cuijuan;Cai, Caihong;Chen, Liangliang;Liu, Shoubai;Zeng, Yanbo;Yuan, Jingzhe;Mei, Wenli;Dai, Haofu

作者机构：

关键词： Acrostichum specioum;mangrove endophyte;Aspergillus fumigatus;anhydride;fatty acid amide;insecticidal activity;antifungal activity

期刊名称：MARINE DRUGS （ 影响因子：5.118； 五年影响因子：5.951 ）

ISSN： 1660-3397

年卷期： 2017 年 15 卷 12 期

页码：

收录情况： SCI

摘要： Fungi residing in mangroves are considered to be a bank of novel bioactive natural products. In the screening for bioactive metabolites from mangrove-derived fungi, the ethyl acetate extract of the fermentation broth of Aspergillus fumigatus JRJ111048, a fungus isolated from the leaves of the mangrove plant Acrostichum specioum endemic to Hainan island, was found to possess insecticidal activity against Spodoptera litura. Bioactivity-guided isolation lead to the discovery of seven metabolites 1-7, including one new anhydride derivative aspergide (1), one new lipid amide 11-methyl-11-hydroxyldodecanoic acid amide (2), and five known compounds; -ethyl glucoside (3), spiculisporic acid B (4), spiculisporic acid C (5), spiculisporic acid (6), and secospiculisporic acid B (7). Their structures were established by NMR spectroscopic and MS analyses, and by comparison of previously reported data. Insecticidal activity against S. litura and antifungal activity of these compounds were investigated. As a result, the new compound 1 showed potent insecticidal activity against newly hatched larvae of S. litura, and compound 4 displayed weak antifungal activity against Candida albicans.

分类号：

  • 相关文献

[1]Design, Synthesis, and Antiviral, Fungicidal, and Insecticidal Activities of Tetrahydro-beta-carboline-3-carbohydrazide Derivatives. Liu, Yongxian,Song, Hongjian,Huang, Yuanqiong,Liu, Yuxiu,Li, Yongqiang,Wang, Qingmin,Li, Jiarui,Yang, Peiwen,Shang, Hui,Song, Yuchuan,Xiao, Zhixin. 2014

[2]Cloning and characterization of a novel Cry1A toxin from Bacillus thuringiensis with high toxicity to the Asian corn borer and other lepidopteran insects. Liang, Gemei,Li, Haitao,He, Kanglai,Song, Fuping,Feng, Xue,Zhang, Jie,Crickmore, Neil,Huang, Dafang.

[3]Insight into Enzymatic Degradation of Corn, Wheat, and Soybean Cell Wall Cellulose Using Quantitative Secretome Analysis of Aspergillus fumigatus. Ghimire, Prakriti Sharma,Ouyang, Haomiao,Yang, Jinghua,Lu, Yang,Jin, Cheng,Ghimire, Prakriti Sharma,Jin, Cheng,Wang, Qian,Luo, Yuanming,Shi, Bo,Ghimire, Prakriti Sharma.

[4]Characterization and identification of the xylanolytic enzymes from Aspergillus fumigatus Z5. Miao, Youzhi,Li, Juan,Shen, Qirong,Zhang, Ruifu,Zhang, Ruifu,Xiao, Zhizhuang. 2015

[5]Genome-wide transcriptomic analysis of a superior biomass-degrading strain of A-fumigatus revealed active lignocellulose-degrading genes. Miao, Youzhi,Liu, Dongyang,Li, Guangqi,Li, Pan,Xu, Yangchun,Shen, Qirong,Zhang, Ruifu,Miao, Youzhi,Liu, Dongyang,Li, Guangqi,Li, Pan,Xu, Yangchun,Shen, Qirong,Zhang, Ruifu,Zhang, Ruifu. 2015

[6]A high throughput method for rapid screening of chitosanase-producing fungal strain under acidic conditions. Chen, Gui-Guang,Liang, Zhi-Qun,Zeng, Wei,Chen, Gui-Guang,Liang, Zhi-Qun,Zeng, Wei,Chen, Gui-Guang,Liang, Zhi-Qun,Zeng, Wei,Cao, Mu-Ming,Chen, Guo-Pin,Xie, Shu-Yu,Li, Wei.

[7]Structure-based fragment shuffling of two fungal phytases for combination of desirable properties. Wang, Xunzhang,Bei, Jinlong,Chen, Zhuang,Jiang, Zongyong.

[8]Study of Synthesis and Biological Activities of a Novel Macrolide Derivatives. Shi Daxin,Feng Xue,Zhuang Xiaolei,Chai Hongxin,Zhang Qi,Li Jiarong,Liu Ting. 2014

[9]Oligomerization of Cry9Aa in solution without receptor binding, is not related with insecticidal activity. Fang, Longfa,Wang, Bo,Zhou, Zishan,Yang, Sujuan,Shu, Changlong,Song, Fuping,Zhang, Jie,Bravo, Alejandra,Soberon, Mario. 2016

[10]Insecticidal action of Quinomycin A from Streptomyces sp KN-0647, isolated from a forest soil. Zhang, Jie,Liu, Huamei,Qin, Sheng,Wang, Yongxia,Li, Wenjun,Qin, Sheng,Wang, Yongxia,Li, Wenjun. 2008

[11]The chitinase C gene PsChiC from Pseudomonas sp and its synergistic effects on larvicidal activity. Zhong, Wanfang,Guo, Huifang,Zhong, Wanfang,Ding, Shaojun. 2015

[12]Design, synthesis and biological evaluation of organophosphorous-homodimers as dual binding site acetylcholinesterase inhibitors. Xie, Ruliang,Zhao, Qianfei,Zhang, Tao,Mei, Xiangdong,Ning, Jun,Fang, Jing,Tang, Yun.

[13]Toxicity of Actinidia chinensis extracts to Plutella xylostella. Chen, Kaoshan,Qi, Junshan,Li, Changsong,Li, Mei.

[14]Khayasin and 2 ' S-methylbutanoylproceranolide: Promising candidate insecticides for the control of the coconut leaf beetle, Brontispa longissima. Li, Min-Yi,Wu, Jun,Zhang, Jing,Feng, Gang,Li, Min-Yi,Satyanandamurty, Tirumani. 2011

[15]Screening of Vip3Aa60 and Vip3Ad5 and characterization of their binding to Spodoptera exigua midguts. Pan, Zhi-Zhen,Guan, Xiong,Xu, Lian,Zhang, Jing,Chen, Qing-Xi,Gao, Huan-Juan,Pan, Zhi-Zhen,Liu, Bo,Chen, Zheng,Zhu, Yu-Jing. 2017

[16]Purification of an active fragment of Cry1Ie toxin from Bacillus thuringiensis. Zhang, Chunlu,Lin, Xiaoyin,Zhang, Yanrui,He, Kanglai,Song, Fuping,Zhang, Jie.

[17]Design, synthesis and insecticidal activity of novel hydrocarbylidene nitrohydrazinecarboximidamides. Yang, Dong-yan,Zhou, Zi-yuan,Ma, Yong-qiang,Qin, Zhao-hai,Zou, Xiang-gao,Rui, Chang-hui.

[18]Design, synthesis and bioactivity evaluation of novel acylthiourea derivatives of cantharidin. Wang, Mei-Juan,Nan, Xiang,Liu, Ying-Qian,Yu, Hai-Tao,Hu, Guan-Fang,Feng, Gang. 2014

[19]Synthesis, Structural Characterization, Insecticidal and Fungicidal Activity of (1H-1,2,4-Triazol-5-yl) carbamatest. Yang Dongyan,Che Chuanliang,Ma Yongqiang,Qin Zhaohai,Rui Changhui,Yan Xiaojing. 2016

[20]Designed biosynthesis of 25-methyl and 25-ethyl ivermectin with enhanced insecticidal activity by domain swap of avermectin polyketide synthase. Yan, Yi-Jun,An, Jing,Wang, Xiang-Jing,Xiang, Wen-Sheng,Xiang, Wen-Sheng,Yan, Yi-Jun,Huang, Sheng-Xiong. 2015

作者其他论文 更多>>

微信小程序