Two unprecedented 5,6,7,8-tetrahydro-2-(2-phenylethyl)chromones with anti-Helicobacter pylori activity from agarwood of Aquilaria sinensis 'Reke 1'
文献类型： 外文期刊
第一作者： Qin, Ke-Xin
作者： Qin, Ke-Xin;Jian, Jie;Qin, Ke-Xin;Wang, Hao;Yang, Li;Wei, Yan-Mei;Cai, Cai-Hong;Chen, Hui-Qin;Dong, Wen-Hua;Li, Wei;Yan, Xian-Yun;Zeng, Jun;Mei, Wen-Li;Dai, Haofu;Qin, Ke-Xin;Wang, Hao;Yang, Li;Wei, Yan-Mei;Cai, Cai-Hong;Chen, Hui-Qin;Dong, Wen-Hua;Li, Wei;Yan, Xian-Yun;Zeng, Jun;Mei, Wen-Li;Dai, Haofu
作者机构：
关键词： Agarwood; Aquilaria sinensis 'Reke 1 '; 2-(2-Phenylethyl)chromone; Anti -Helicobacter pylori activity
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.4； 五年影响因子：1.5 ）
ISSN： 1874-3900
年卷期： 2025 年 66 卷
页码：
收录情况： SCI
摘要： Two new 5,6,7,8-tetrahydro-2-(2-phenylethyl)chromones (1 and 2), together with one known compound (3), were isolated from the ethanol extract of agarwood produced from Aquilaria sinensis 'Reke 1'. The structures of compounds 1 and 2 were precisely elucidated on the basis of HR-ESI-MS, 1D and 2D NMR, TDDFT-ECD, as well as by comparison with the literature data. All compounds were evaluated for anti-Helicobacter pylori activity. Compound 2 exhibited significant inhibitory effect against H. pylori with the minimum inhibition concentration (MIC) value of 20 mu M.
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