A new cytotoxic iridoid from Callicarpa nudiflora

文献类型： 外文期刊

第一作者： Mei, Wen-Li

作者： Mei, Wen-Li;Han, Zhuang;Cui, Hai-Bin;Deng, Yuan-Yuan;Dai, Hao-Fu;Zhao, You-Xing

作者机构：

关键词： Callicarpa nudiflora;iridoid;nudifloside;cytotoxicity

期刊名称：NATURAL PRODUCT RESEARCH （ 影响因子：2.861； 五年影响因子：2.572 ）

ISSN： 1478-6419

年卷期： 2010 年 24 卷 10 期

页码：

收录情况： SCI

摘要： A new iridoid, named nudifloside (1), together with three known compounds, was isolated from the EtOH extract of the aerial parts of Callicarpa nudiflora Hook. The structures were elucidated by a study of their physical and spectral data. Nudifloside (1) and the isolated known compound linearoside (2) displayed inhibitory effects towards chronic myelogenous leukaemia K562 cell line, with IC50 values of 20.7 and 36.0 mu g mL-1, respectively.

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