A novel antibiotic produced by streptomyces noursei Da07210

文献类型: 外文期刊

第一作者: Wu, Xiaopeng

作者: Wu, Xiaopeng;Huang, Huiqin;Sun, Qianguang;Peng, Jie;Zhu, Jun;Bao, Shixiang;Chen, Guangying

作者机构:

关键词: Antifungal activity;Fungicide;Antitumor activity;Actinomycete

期刊名称:ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY ( 影响因子:2.271; 五年影响因子:2.707 )

ISSN: 0003-6072

年卷期: 2009 年 96 卷 1 期

页码:

收录情况: SCI

摘要: A novel antibiotic 210-A, named as (6S,8aS,9S,11S,12aR)-6-hydroxy-9,10-dimethyldecahydrobenzo[d]azecine-2,4,12(3H)-trione, was isolated from the fermentation broth of Streptomyces noursei Da07210, its structure was unambiguously established by spectral analyses and chemical comparison with related cycloheximide. Experiments demonstrated that 210-A bore strong activity against Fusarium oxysporum f. sp. cubense race four (Foc race four), which also showed antitumor activity against SMMC-7721 human hepatocarcinoma cells and S180 murine sarcoma, and the IC(50) values were 0.77 and 0.74 mu g/ml, respectively.

分类号:

  • 相关文献

[1]A new fungicide produced by a Streptomyces sp GAAS7310. Chen, GY,Lin, BR,Lin, YC,Xie, FC,Lu, W,Fong, WF. 2005

[2]Antimycins A(19) and A(20), two new antimycins produced by marine actinomycete Streptomyces antibioticus H74-18. Xu, Lin-Ya,Quan, Xue-Sheng,Zhou, Guang-Xiong,Jiang, Ren-Wang,Yao, Xin-Sheng,Wang, Chen,Sheng, Hui-Fang,Lin, Bi-Run. 2011

[3]Design, Synthesis and Bioactivity of N-Glycosyl-N '-(5-substituted phenyl-2-furoyl) Hydrazide Derivatives. Cui, Zining,Nishida, Yoshihiro,Su, Hang,Jiang, Jiazhen,Yang, Xinling,Cui, Zining. 2014

[4]Molecular design, synthesis and bioactivity of glycosyl hydrazine and hydrazone derivatives: Notable effects of the sugar moiety. Cui, Zining,Dohi, Hirofumi,Nishida, Yoshihiro,Cui, Zining,Yang, Xinling,Shi, Yanxia,Uzawa, Hirotaka,Cui, Jingrong. 2011

[5]Synthesis and Bioactivities of Novel Pyrazole and Triazole Derivatives Containing 5-Phenyl-2-Furan. Cui, Zi-Ning,Ling, Yun,Yang, Xin-Ling,Shi, Yan-Xia,Li, Bao-Ju,Cui, Jing-Rong. 2012

[6]Synthesis and Bioactivity of Novel Carvacrol and Thymol Derivatives Containing 5-Phenyl-2-furan. Li, Xinghai,Cui, Zining,Nishida, Yoshihiro,Cui, Zining. 2014

[7]New Cytotoxic Alkylated Anthraquinone Analogues from a Soil Actinomycete Streptomyces sp WS-13394. Wu, Zhao-Yuan,Fang, Wei,Shi, Li-Qiao,Wan, Zhong-Yi,Min, Yong,Wang, Kai-Mei. 2014

[8]Four new anthraquinones from a soil actinomycete Streptomyces sp WS-13394 and their bioactivities. Wu, Zhaoyuan,Zhang, Yani,Fang, Wei,Shi, Liqiao,Wan, Zhongyi. 2018

[9]Effect of nutritional and environmental conditions on the production of exo-polysaccharide of Agaricus brasiliensis by submerged fermentation and its antitumor activity. Fan, Leifa,Soccol, Andrea Thomaz,Pandey, Ashok,Soccol, Carlos Ricardo. 2007

[10]Optimization of Enzyme-assisted Extraction of Antitumor Polysaccharides from Hericium erinaceus mycelia. Qin, Yi,Zhang, Zuofa,Song, Tingting,Lv, Guoying.

[11]Discovery of novel isatin-dehydroepiandrosterone conjugates as potential anticancer agents. Ke, Shaoyong,Shi, Liqiao,Yang, Ziwen.

[12]Antioxidant and Cytotoxic Activities of Ethanolic Extracts and Isolated Fractions of Species of the Genus Phellinus Quel. (Aphyllophoromycetideae). Yang, Yan,Hu, Jinxia,Liu, Yanfang,Feng, Na,Chen, Hui,Tang, Qingjiu,Zhang, Jingsong,Ye, LinBin. 2011

[13]Synthesis and in vitro antitumor activity of (1E, 4E)-1-aryl-5-(2-(( quinazolin-4-yl) oxy) phenyl)-1,4-pentadien-3-one derivatives. Luo, Hui,Xie, Pu,Yang, Shengjie,Hong, Da,Luo, Hui,Yang, Shengjie,Xue, Wei,Luo, Hui,Yang, Shengjie,Xue, Wei. 2017

[14]Chemical Characterization of a Procyanidin-Rich Extract from Sorghum Bran and Its Effect on Oxidative Stress and Tumor Inhibition in Vivo. Wu, Li,Huang, Zhaohui,Qin, Peiyou,Yao, Yang,Ren, Guixing,Huang, Zhaohui,Meng, Xianjun,Zou, Jianqiu,Zhu, Kai.

[15]Immunoregulatory and antitumor activity of schizophyllan under ultrasonic treatment. Zhong, Kui,Tong, Litao,Liu, Liya,Zhou, Xianrong,Liu, Xingxun,Zhang, Qi,Zhou, Sumei,Zhong, Kui,Tong, Litao,Liu, Liya,Zhou, Xianrong,Liu, Xingxun,Zhang, Qi,Zhou, Sumei.

[16]Synthesis and biological activities of 2-oxocycloalkylsulfonamides. Yang, Xinling,Liang, Xiaomei,Kai, Zhenpeng,Yuan, Dekai,Zhang, Jianjun,Ling, Yun,Chen, Fuheng,Wang, Daoquan,Yuan, Huizu,Qi, Shuhua,Wang, Ruiqing,Ran, Fuxiang. 2008

[17]Synthesis, antitumor activity and mechanism of action of novel 1,3-thiazole derivatives containing hydrazide-hydrazone and carboxamide moiety. He, Haifeng,Wang, Xiaoyan,He, Hongwu,Shi, Liqiao,Yin, Wenyan,Yang, Ziwen,Liang, Ying. 2016

[18]Synthesis of Novel Steroid Derivatives Derived from Dehydroepiandrosterone as Potential Anticancer Agents. Ke, Shaoyong,Shi, Liqiao,Yang, Qingyu,Yang, Ziwen,Wei, Yanhong,Yang, Ziwen. 2013

[19]Antitumor Compounds from the Stout Camphor Mushroom Taiwanofungus camphoratus (Higher Basidiomycetes) Spent Culture Broth. Jia, Wei,Bai, Yan-Yan,Zhang, Zhong,Feng, Na,Feng, Jie,Yan, Meng-Qiu,Zhu, Li-Na,Zhang, Jing-Song,Fan, Hua,Bai, Yan-Yan,Jia, Xin-Cheng,Wang, Ming-Dao,Fan, Hua.

[20]Anthranilic acid-based diamides derivatives incorporating aryl-isoxazoline pharmacophore as potential anticancer agents: Design, synthesis and biological evaluation. Shi, Liqiao,Hui, Rui,Wei, Yanhong,Liang, Ying,Yang, Ziwen,Ke, Shaoyong.

作者其他论文 更多>>