文献类型： 外文期刊
作者： Zheng, Jinkai 1 ; Zhu, Huajie 2 ; Hong, Kui 3 ; Wang, Yi 1 ; Liu, Peipei 1 ; Wang, Xin 1 ; Peng, Xiaoping 1 ; Zhu, Weimin 1 ;
作者机构： 1.Ocean Univ China, Key Lab Marine Drugs, Chinese Minist Educ, Sch Med & Pharm, Qingdao 266003, Peoples R China
2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources, Kunming Inst Bot, Kunming 650204, Peoples R China
3.Chinese Acad Trop Agr Sci, Inst Trop Biol Sci & Biotechnol, Haikou 571101, Peoples R China
关键词： ALKALOIDS;CYCLOPEPTIDES;ASSAY
期刊名称：ORGANIC LETTERS （ 影响因子：6.005； 五年影响因子：5.551 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： Two novel cyclic hexapeptides containing both anthranilic acid and dehydroamino acid units, sclerotides A (1) and B (2), were isolated from the marine-derived halotolerant Aspergillus sclerotiorum PT06-1 in a nutrient-limited hypersaline medium. Both 1 and 2 are photointerconvertible and could be interconverted via a radical reaction Initiated by direct photoisomerization. Both compounds showed moderate antifungal activity. Compound 2 also showed weak cytotoxicity and antibacterial activity.
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