Preparation of novel self-assembled albumin nanoparticles from Camellia seed cake waste for lutein delivery
文献类型： 外文期刊
作者： Yu, Ningxiang 1 ; Shao, Shengxin 1 ; Huan, Weiwei 2 ; Ye, Qin 3 ; Nie, Xiaohua 1 ; Lu, Yuanchao 1 ; Meng, Xianghe 1 ;
作者机构： 1.Zhejiang Univ Technol, Coll Food Sci & Technol, Hangzhou 310014, Zhejiang, Peoples R China
2.Zhejiang A&F Univ, Coll Chem & Mat Engn, Hangzhou 311300, Zhejiang, Peoples R China
3.Zhejiang Acad Agr Sci, Inst Food Sci, Hangzhou 310014, Zhejiang, Peoples R China
关键词： Camellia seed cake; Albumin; Nanoparticles; Delivery system; Lutein
期刊名称：FOOD CHEMISTRY （ 影响因子：9.231； 五年影响因子：8.795 ）
ISSN： 0308-8146
年卷期： 2022 年 389 卷
页码：
收录情况： SCI
摘要： The potential utilization value of Camellia seed cake was explored by extracting albumin (CSCA) to develop nanoparticles for lutein delivery. First, thermal property and amphiphilicity of CSCA were evaluated to guide nanoparticle preparation. Next, CSCA nanoparticles modified with chitosan (CS) were prepared through a thermally induced self-assembly method derived by electrostatic attraction and hydrophobic interaction. The optimized nanoparticles were prepared from CSCA:CS at a mass ratio of 2:1 with pH of 4.5, and an incubation temperature and time of 80 celcius and 10 min, respectively. The nanoparticles had the highest effective loading capacity for lutein at 5.89 +/- 0.78%, and the corresponding encapsulation efficiency was 43.82 +/- 5.69%. The storage stability of lutein was improved by nanoparticle loading, and the bioaccessibility of lutein in simulated intestinal digestion increased from 26.8 +/- 4.4% to 57.3 +/- 9.6% after encapsulation into nanoparticles. These findings may facilitate the development of new and sustainable proteins from plant waste for delivery system applications.
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