Development of composite nanoparticles from gum Arabic and carboxymethylcellulose-modified Stauntonia brachyanthera seed albumin for lutein delivery
文献类型: 外文期刊
作者: Yu, Ningxiang 1 ; Wang, Jinshuang 1 ; Jiang, Chengjia 2 ; Nie, Xiaohua 1 ; Hu, Zhenying 2 ; Ye, Qin 3 ; Meng, Xianghe 1 ; Xiong, Hua 2 ;
作者机构: 1.Zhejiang Univ Technol, Coll Food Sci & Technol, Hangzhou 310014, Zhejiang, Peoples R China
2.Nanchang Univ, State Key Lab Food Sci & Technol, 235 Nanjing East Rd, Nanchang 330047, Jiangxi, Peoples R China
3.Zhejiang Acad Agr Sci, Inst Food Sci, Hangzhou 310014, Peoples R China
关键词: Stauntonia brachyanthera seed; Albumin; Nanoparticles; Delivery system; Lutein; Bioaccessibility
期刊名称:FOOD CHEMISTRY ( 影响因子:9.231; 五年影响因子:8.795 )
ISSN: 0308-8146
年卷期: 2022 年 372 卷
页码:
收录情况: SCI
摘要: Lutein is a carotenoid with several beneficial functions, but its poor water solubility, chemical instability, and low bioavailability limits its application. To overcome these shortcomings, self-assembly composite nanoparticles from Stauntonia brachyanthera seed albumin (SBSA), gum Arabic (GA), and carboxymethylcellulose (CMC) were developed for lutein encapsulation. Firstly, SBSA was extracted from seeds and its physicochemical properties were evaluated. Followingly, the nanoparticles were prepared with SBSA through a heat induced self-assembly method which were modified by GA and CMC. The nanoparticles exhibited good storage, pH, and salt stability. Hydrogen bonds, hydrophobic interactions, and electrostatic interactions were proved to derive the formation of nanoparticles. The maximum effective loading capacity (LC) of the lutein in nanoparticles was 0.92 +/- 0.01% with an encapsulation efficiency (EE) at 83.95 +/- 0.98%. Heat stability and storage stability of lutein were significantly enhanced after encapsulation into nanoparticles. In addition, the bioaccessibility of lutein increased from 17.50 +/- 2.60% to 46.80 +/- 4.70% after encapsulation into nanoparticles.
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