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Research Progress and Trends of Phenylethanoid Glycoside Delivery Systems

文献类型： 外文期刊

作者： Huang, Jin 1 ; Zhao, Dandan 1 ; Cui, Chaojing 1 ; Hao, Jianxiong 1 ; Zhang, Zhentao 2 ; Guo, Limin 3 ;

作者机构： 1.Hebei Univ Sci & Technol, Coll Food Sci & Biol, Shijiazhuang 051432, Hebei, Peoples R China

2.Tech Inst Phys & Chem CAS, Beijing 100190, Peoples R China

3.Xinjiang Acad Agr Sci, Inst Agroprod Storage & Proc, Urumqi 830091, Peoples R China

关键词： drug delivery; phenylethanoid glycoside; bioavailability; biological activity; nanoemulsion; liposome; nanoparticle

期刊名称：FOODS （ 影响因子：5.561； 五年影响因子：5.94 ）

ISSN：

年卷期： 2022 年 11 卷 5 期

页码：

收录情况： SCI

摘要： Background: Phenylethanoid glycosides (PhGs) are obtained from a wide range of sources and show strong biological and pharmacological activities, such as antioxidant, antibacterial and neuroprotective effects. However, intestinal malabsorption and the low bioavailability of PhGs seriously affect their application. Delivery systems are an effective method to improve the bioavailability of active substances. Scope and approach: In this article, the biological activities of and delivery systems for PhGs are introduced. The application statuses of delivery systems for echinacoside, acteoside and salidroside are reviewed. Finally, the problems of the lack of uniform standards for delivery systems and the poor targeted delivery accuracy of PhGs in the current research are proposed and suggestions for future research are put forward based on those problems. Key findings and conclusions: Although there are still some problems in the delivery system of phenylethanoside, such as inconsistent standards and inaccurate delivery, phenylethanoside itself has been proven to have a variety of physiological activities. Therefore, the action mechanism and application of phenylethanoside and its delivery system should be studied further.

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