您好，欢迎访问中国热带农业科学院 机构知识库！
中国热带农业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Polysaccharides from Artocarpus heterophyllus Lam. (jackfruit) pulp alleviate obesity by modulating gut microbiota in high fat diet-induced rats

文献类型： 外文期刊

作者： Zeng, Shunjiang 1 ; Cao, Jun 2 ; Wei, Chenxi 3 ; Chen, Yuzi 4 ; Liu, Qibing 5 ; Li, Chuan 2 ; Zhang, Yanjun 1 ; Zhu, Kexue 1 ; Wu, Gang 1 ; Tan, Lehe 1 ;

作者机构： 1.Chinese Acad Trop Agr Sci, Spice & Beverage Res Inst, Wanning 571533, Hainan, Peoples R China

2.Hainan Univ, Coll Food Sci & Engn, Haikou 570228, Hainan, Peoples R China

3.Jilin Agr Univ, Coll Food Sci & Engn, Changchun 130118, Jilin, Peoples R China

4.Hua Zhong Agr Univ, Coll Food Sci & Technol, Wuhan 430070, Hubei, Peoples R China

5.Hainan Med Univ, Sch Basic Med & Life Sci, Dept Pharmacol, Haikou 571199, Hainan, Peoples R China

6.Key Lab Proc Suitabil & Qual Control Special Trop, Wanning 571533, Hainan, Peoples R China

7.CATAS, Spice & Beverage Res Inst, Wanning 571533, Hainan, Peoples R China

关键词： Obesity; Intestinal flora; Artocarpus heterophyllus Lam; Polysaccharide

期刊名称：FOOD HYDROCOLLOIDS （ 影响因子：10.7； 五年影响因子：10.9 ）

ISSN： 0268-005X

年卷期： 2023 年 139 卷

页码：

收录情况： SCI

摘要： Polysaccharides have attracted widely attention for their ability to alleviate obesity by regulating intestinal flora. The modulating effect of polysaccharides from Artocarpus heterophyllus Lam. (jackfruit) pulp (JFP-Ps) on the intestinal flora and body weight (BW) in obese individuals remains unclear. The present study aimed to inves-tigate the regulatory effects of JFP-Ps on intestinal flora in obese rats. The obese rat model was established by continuous induction of high-fat diet for 12 weeks, and then changes in intestinal flora were determined by 16S rRNA sequencing after JFP-Ps intervention. Results showed that JFP-Ps restrained BW gain, improved serum lipid profile, increased number of operational taxonomic units, species abundance and diversity, modulated the composition of intestinal flora, and reversed the dysbiosis of intestinal flora caused by high-fat diet. Moreover, JFP-Ps restored intestinal microecology and enhanced the antioxidant capacity of obese rats by increasing the abundance of short-chain fatty acids-producing bacteria (Prevotellaceae_Ga6A1_group, Sphaerochaeta and Allo-prevotella) and reactive sulfur species-producing bacterium (Ruminococcaceae). These findings reveal that JFP-Ps may be a promising prebiotic for the treatment of obesity by modulation of intestinal flora.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国热带农业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台