Protection of Chickens from Newcastle Disease and Infectious Laryngotracheitis with a Recombinant Fowlpox Virus Co-Expressing the F, HN Genes of Newcastle Disease Virus and gB Gene of Infectious Laryngotracheitis Virus
文献类型： 外文期刊
作者： Sun, Hui-Ling 1 ; Wang, Yun-Feng 2 ; Tong, Guang-Zhi 1 ; Zhang, Pei-Jun 3 ; Miao, De-Yuan 3 ; Zhi, Hai-Dong 2 ; Wang, 1 ;
作者机构： 1.China Agr Univ, Beijing 100094, Peoples R China
2.CAAS, Harbin Vet Res Inst, Natl Key Lab Vet Biotechnol, Harbin 150001, Peoples R China
3.Beijing Acad Agr & Forestry Sci, Inst Anim Husb & Vet Sci, Beijing 100089, Peoples R China
期刊名称：AVIAN DISEASES （ 影响因子：1.577； 五年影响因子：1.915 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： A recombinant fowlpox virus (rFPV) coexpressing the Newcastle disease virus (NDV) fusion and hemagglutinin-neuraminidase genes and infectious laryngothracheitis virus (ILTV) glycoprotein B gene was constructed. This virus was then evaluated for its ability to protect specific-pathogen-free (SPF) chickens against clinical symptoms and death after challenge by virulent NDV and ILTV. SPF chickens were grouped and vaccinated with the rFPV and commercial NDV (La Sota) and ILTV attenuated live vaccine (Nobilis ILT), respectively. After challenge with NDV 10 days postvaccination, 70% of chickens vaccinated with rFPV were protected from death, whereas 100% of the commercial NDV-vaccinated chickens were protected from death. In contrast, 100% of the unvaccinated chickens died after challenge. After challenge with ILTV, both the rFPV and commercial ILTV-vaccinated chickens were completely protected from death and 70% of chickens were protected from respiratory signs. In comparison, 100% of the unvaccinated chickens developed severe respiratory disease and 10% of chickens died. The protective efficacy was also measured by the antibody responses and isolation of challenge viruses. Results showed that this rFPV could be a potential vaccine for preventing NDV and ILTV by a single immunization.
- 相关文献
作者其他论文 更多>>
-
Advancements of UAV and Deep Learning Technologies for Weed Management in Farmland
作者：Zhang, Jinmeng;Yu, Feng;Zhang, Qian;Wang, Ming;Yu, Jinying;Tan, Yarong;Yu, Feng
关键词：unmanned aerial vehicle; convolutional neural network; deep learning; weed detection; weed management
-
Advancements in Utilizing Image-Analysis Technology for Crop-Yield Estimation
作者：Yu, Feng;Xiao, Jun;Yu, Feng;Wang, Ming;Zhang, Qian;Zhang, Jinmeng;Liu, Xin;Ping, Yang;Luan, Rupeng
关键词：remote sensing images; visible light images; machine learning; deep learning; biomass; yield calculation
-
Progress in the Application of CNN-Based Image Classification and Recognition in Whole Crop Growth Cycles
作者：Yu, Feng;Xiao, Jun;Yu, Feng;Zhang, Qian;Ma, Yuntao;Wang, Ming;Luan, Rupeng;Liu, Xin;Ping, Yang;Nie, Ying;Tao, Zhenyu;Zhang, Hui
关键词：convolution neural network; crop classification; crop recognition; whole crop growth cycle
-
Safety, Immunogenicity, and Effectiveness of Defective Viral Particles Arising in Mast Cells Against Influenza in Mice
作者：Huo, Caiyun;Tian, Jijing;Cheng, Jinlong;Chen, Mingyong;Tian, Haiyan;Wang, Ming;Hu, Yanxin;Huo, Caiyun;Sun, Huiling;Xiao, Jin;Zou, Shumei
关键词：mast cells; defective viral particles; immunogenicity; protective immune reaction
-
Mobile Phone Application of Agricultural Resources and Environment Information Based on Agricultural Short Message Service Content
作者：Hu, Yanxiang;Sun, Lixin;Liu, Xin;Ping, Yang;Wang, Ming
关键词：
-
Identification and sequence analysis of aroA gene of avibacterium paragallinarum
作者：Lv, Xue-Ze;Wang, Hong-Jun;Chen, Xiao-Ling;Gong, Yu-Mei;Liang, Yu-Rong;He, Yun-Xia;Zhang, Pei-Jun
关键词：Apg;aroA;gene identification;protein structure;molecule evolution
-
Genome-wide association study (GWAS) of resistance to head smut in maize
作者：Wang, Ming;Yan, Jianbing;Zhang, Xiaobo;Xiao, Yannong;Zheng, Yonglian;Zhao, Jiuran;Song, Wei
关键词：MaizeSNP50;Genome-wide association study;Head smut;Zea mays
