您好，欢迎访问内蒙古农牧业科学院 机构知识库！
内蒙古农牧业科学院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Selection signature analysis reveals genes associated with tail phenotype in sheep

文献类型： 外文期刊

作者： Qi, Yunxia 1 ; He, Xiaolong 2 ; Wang, Biao 2 ; Yang, Chaoyun 1 ; Da, Lai 2 ; Liu, Bin 3 ; Zhang, Wenguang 4 ; Fu, Shaoyin 2 ; Liu, Yongbin 2 ;

作者机构： 1.Xichang Univ, Coll Anim Sci, Xichang, Peoples R China

2.Inner Mongolia Acad Agr & Anim Husb Sci, Anim Husb Inst, Hohhot, Peoples R China

3.Inner Mongolia Bionew Technol Co Ltd, Hohhot, Peoples R China

4.Inner Mongolia Agr Univ, Coll Life Sci, Hohhot, Peoples R China

5.Inner Mongolia Univ, Coll Life Sci, State Key Lab Reprod Regulat & Breeding Grassland, Hohhot, Peoples R China

关键词： sheep; tail type; selection signature analysis; F-ST; pi-ratio; XP-EHH

期刊名称：FRONTIERS IN GENETICS （ 影响因子：2.8； 五年影响因子：3.3 ）

ISSN：

年卷期： 2024 年 15 卷

页码：

收录情况： SCI

摘要： Tail type of sheep, which may be affected by many genes with a complex mechanism, is an important economic trait concerned by both raiser and consumers. Here, we employed two sheep breeds with extreme phenotypes - Mongolian sheep (short-fat-tailed) and Bamei Mutton sheep (long-thin-tailed) to analyze the genetic differences at the genomic level and find candidate genes associated with tail phenotype. The results of population structure analysis showed that the LD decay rate of Mongolian sheep was greater than that of Bamai Mutton sheep. When K = 2, the two populations were obviously separated with a certain degree of mixing. From 49 sheep individuals, 20,270,930 and 2,479,474 SNPs and Indels were identified, respectively. Selection signals were detected based on F- ST , pi-Ratio, and XP-EHH. These three methods identified 85 candidate genes, of which PDGFD, GLIS1, AR, and FGF9 were reported to be associated with tail fat deposition, while VRTN associated with tail length in sheep tail phenotype; the others were novel genes that may play important roles in sheep tail phenotype formation. Gene annotation revealed that these candidate genes mainly participate in pathways associated with fat deposition or lipid metabolism. This study provided insight into sheep tail type development and a guide for molecular breeding.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：内蒙古农牧业科学院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台