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Combination of untargeted metabolomics approach and molecular networking analysis to identify unique natural components in wild Morchella sp. by UPLC-Q-TOF-MS

文献类型： 外文期刊

作者： Zhao, Xiaoyan 1 ; Hengchao, E. 2 ; Dong, Hui 2 ; Zhang, Yanmei 2 ; Qiu, Jing 1 ; Qian, Yongzhong 1 ; Zhou, Changyan 2 ;

作者机构： 1.Chinese Acad Agr Sci, Inst Qual Stand & Testing Technol Agroprod, Key Lab Agrifood Qual & Safety, Minist Agr & Rural Affairs, Beijing 100081, Peoples R China

2.Shanghai Acad Agr Sci, Inst Agrofood Stand & Testing Technol, Lab Qual & Safety Risk Assessment Agroprod Shangh, Minist Agr & Rural Affairs, 1000 Jingqi Rd, Shanghai 201403, Peoples R China

关键词： Untargeted metabolomics approach; UPLC-Q-TOF-MS; Molecular networking analysis; Hydroxamate siderophore compounds; Morchella sp

期刊名称：FOOD CHEMISTRY （ 影响因子：9.231； 五年影响因子：8.795 ）

ISSN： 0308-8146

年卷期： 2022 年 366 卷

页码：

收录情况： SCI

摘要： Morchella sp. is a typical edible fungus. However, its unique natural products, especially bioactive composition, are rarely reported. In this study, an untargeted metabolomics approach combined with multivariate statistical analysis was employed to screen the differential metabolites in Morchella sp. compared to four other edible fungi. Among the screened 50-top differential metabolites, 18 compounds involving fatty acids and peptides showed higher content in Morchella sp.. A unique peptide of desferriferricrocin was identified. Subsequently, molecular networking analysis revealed three novel homologous compounds of desferriferricrocin, which were annotated as desferriferrichrome, desferriferrichrome C, and a new homolog not previously reported. These results were further verified by quantitative analysis. To the best of our knowledge, this is the first report of four peptides in Morchella sp..

  • 相关文献

[1]Combination of untargeted metabolomics approach and molecular networking analysis to identify unique natural components in wild Morchella sp. by UPLC-Q-TOF-MS. Zhao, Xiaoyan,Qiu, Jing,Qian, Yongzhong,Zhao, Xiaoyan,Hengchao, E.,Dong, Hui,Zhang, Yanmei,Zhou, Changyan. 2022

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