Genome-wide SNPs and indels characteristics of three chinese domestic sheep breeds from different ecoregions
文献类型： 外文期刊
作者： Ma, Lina 1 ; Li, Yingkang 1 ; Ma, Xiaoming 1 ; Eer, Hehua 1 ;
作者机构： 1.Ningxia Acad Agr & Forestry Sci, Inst Anim Sci, Yinchuan 750000, Ningxia, Peoples R China
关键词： Whole-genome resequencing; Chinese domestic sheep; Reproductive processes; Immune
期刊名称：LIVESTOCK SCIENCE （ 影响因子：1.943； 五年影响因子：2.252 ）
ISSN： 1871-1413
年卷期： 2020 年 240 卷
页码：
收录情况： SCI
摘要： Whole-genome resequencing is useful for identifying genetic variations for phenotypic diversity and for revealing the in-depth genomic characteristics associated with adaptation to various ecoregions. Adaptability traits in a diverse range of ecological environments are key to the survival of sheep. Mongolian sheep and its subspecies (Hu sheep and Tan sheep) differ in a number of important traits, especially reproductive traits; however, the potential genetic information still uncertain. In this study we performed pooled whole-genome resequencing of 52 sheep samples (20 Mongolian sheep, 20 Hu sheep and 12 Tan sheep) distributed in different ecoregions to examine the genetic variation. We report genome characterization of three native Chinese domestic sheep breeds discovering 3,537,483 SNPs and 47,890 InDels using whole genome resequencing. The present study emphasizes the genetic diversity, extending our previous study. The genomic regions related to reproductive processes and immune system process of the stress responses according to GO analysis. Altogether, we found reproductive related genes (BMPRIB, BMP15, GDF9 and MTNRIA) and immune related genes (PGLYRP2, TRIM15, TRIM40, SOCS7 and TFAM) in the three sheep breeds. Our results provide a valuable resource of the genomic information for identifying genes associated with important economic traits in sheep and for understanding the genetic characteristics of adaptation to different ecological environments.
- 相关文献
作者其他论文 更多>>
-
Mining key circRNA-associated-ceRNA networks for milk fat metabolism in cows with varying milk fat percentages
作者：Feng, Xiaofang;Tong, Lijia;Yu, Baojun;Ma, Ruoshuang;Li, Jiwei;Wang, Chuanchuan;Zhang, Juan;Gu, Yaling;Ma, Lina;Mu, Tong
关键词：Dairy cows; circRNAs; Milk fat percentage; WGCNA; ceRNAs
-
Study on the expression patterns of inner root sheath-specific genes in Tan sheep hair follicle during different developmental stages
作者：Shi, An;Lv, Jiangjiang;Tao, Jinzhong;Ma, Qing;Ma, Lina;Liu, Zhanfa;Zhou, Junsheng
关键词：Tan sheep; Inner root sheath; Keratin; Trichohyalin; Temporal expression
-
Epigenetic mechanism of Gtl2-miRNAs causes the primitive sheep characteristics found in purebred Merino sheep
作者：Wang, Jiankui;Hua, Guoying;Chen, Jianfei;Cui, Kai;Yang, Zu;Han, Deping;Yang, Xue;Dong, Xianggui;Ma, Yuhao;Cai, Ganxian;Zhang, Yuanyuan;Li, Jinnan;Tai, Yurong;Wu, Keliang;Zhao, Yaofeng;Deng, Xuemei;Wang, Jiankui;Hua, Guoying;Chen, Jianfei;Cui, Kai;Yang, Zu;Han, Deping;Yang, Xue;Dong, Xianggui;Ma, Yuhao;Cai, Ganxian;Zhang, Yuanyuan;Li, Jinnan;Tai, Yurong;Wu, Keliang;Zhao, Yaofeng;Deng, Xuemei;Wang, Jiankui;Hua, Guoying;Chen, Jianfei;Cui, Kai;Yang, Zu;Han, Deping;Yang, Xue;Dong, Xianggui;Ma, Yuhao;Cai, Ganxian;Zhang, Yuanyuan;Li, Jinnan;Tai, Yurong;Wu, Keliang;Zhao, Yaofeng;Deng, Xuemei;Cui, Kai;Da, Lai;Rong, Weiheng;Li, Rui;Li, Xinhai;Ma, Lina;Ma, Qing;Liu, Jianbin;Darwish, Hesham Y. A.;Liu, Wansheng
关键词：Imprinted gene; Gtl2; PI3K; AKT; mTOR-ROS signaling; REDOX imbalance; Ancestral-like wool; Primary hair follicle
-
Imprinted Dlk1-Gtl2 cluster miRNAs are potential epigenetic regulators of lamb fur quality
作者：Zhang, Letian;Wang, Jiankui;Cai, Ganxian;Deng, Xuemei;Zhang, Letian;Wang, Jiankui;Cai, Ganxian;Deng, Xuemei;Zhang, Letian;Wang, Jiankui;Cai, Ganxian;Deng, Xuemei;Ma, Lina;Zhao, Zhengwei;Ma, Qing
关键词：Dlk1-Gtl2; Tan sheep; Hu sheep; fur; miRNA-seq; PI3K-AKT
-
Whole-genome DNA methylation profiling reveals epigenetic signatures in developing muscle in Tan and Hu sheep and their offspring
作者：Yue, Caijuan;Liu, Yisha;Zhang, Qiao-e;Yue, Caijuan;Zhang, Junli;Liu, Jian;Eer, Hehua;Wang, Jiakang;Shen, Yifei;Xiao, Aiping
关键词：sheep; muscle development; DNA methylation; whole-genome bisulfite sequencing; epigenetics
-
Transcriptome Profiling of Developing Ovine Fat Tail Tissue Reveals an Important Role for MTFP1 in Regulation of Adipogenesis
作者：Han, Jiangang;Liang, Benmeng;Bai, Tianyou;Zhao, Yuhetian;Ma, Yuehui;Jiang, Lin;Han, Jiangang;MacHugh, David E.;Ma, Sijia;Liang, Benmeng;Bai, Tianyou;Zhao, Yuhetian;Ma, Yuehui;Jiang, Lin;MacHugh, David E.;Ma, Lina
关键词：MTFP1; fat tail development; adipogenesis; RNA-seq; mitochondrion
-
Transcriptome Profiling of Developing Ovine Fat Tail Tissue Reveals an Important Role for MTFP1 in Regulation of Adipogenesis
作者：Han, Jiangang;Liang, Benmeng;Bai, Tianyou;Zhao, Yuhetian;Ma, Yuehui;Jiang, Lin;Han, Jiangang;MacHugh, David E.;Ma, Sijia;Liang, Benmeng;Bai, Tianyou;Zhao, Yuhetian;Ma, Yuehui;Jiang, Lin;MacHugh, David E.;Ma, Lina
关键词：MTFP1; fat tail development; adipogenesis; RNA-seq; mitochondrion
