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Fabrication of ovalbumin-burdock polysaccharide complexes as interfacial stabilizers for nanostructured lipid carriers: Effects of high-intensity ultrasound treatment

文献类型: 外文期刊

作者: Wu Shanshan 1 ; Huang Meigui 2 ; Li Chunyang 1 ; Chai Zhi 1 ; Cui Li 1 ; Huang Wuyang 1 ; Li Ying 1 ; Feng Jin 1 ;

作者机构: 1.Jiangsu Acad Agr Sci, Inst Agroprod Proc, 50 Zhongling St, Nanjing 210014, Peoples R China

2.Nanjing Forestry Univ, Coll Light Ind & Food Engn, Dept Food Sci & Engn, 159 Longpan Rd, Nanjing 210037, Peoples R China

3.Zhejiang Univ, Dept Food Sci & Nutr, 866 Yuhangtang Rd, Hangzhou 310058, Peoples R China

关键词: Ovalbumin; Burdock polysaccharides; Nanostructured lipid carriers; High-intensity ultrasound treatment; Curcumin

期刊名称:FOOD HYDROCOLLOIDS ( 影响因子:9.147; 五年影响因子:9.169 )

ISSN: 0268-005X

年卷期: 2021 年 111 卷

页码:

收录情况: SCI

摘要: Ovalbumin (OVA)-burdock polysaccharide complex emulsifiers were prepared in this work by high-intensity ultrasound (HIU) treatment for nanostructured lipid carriers (NLCs) stabilization. HIU treatment remarkably changed their physicochemical properties and resulted in the cross-linking between these two biopolymers. The diffusion rate of the stabilizers towards oil-water interface and their dilatational elastic modulus increased with increasing ultrasound power at first, reaching a maximum at 400 W cm(-2), and decreased thereafter. Therefore, Biopolymers treated with 400 W cm(-2) energy intensity were most effective in preventing the polymorphic transition of NLCs and degradation of encapsulated curcumin (Cur) because they assembled a compact interfacial layer that blocked the motion of carrier oil. Moreover, they also contributed to a more sustainable Cur release in the simulated gastrointestinal tract. Cur in NLCs presented remarkably higher cellular antioxidant capacity and ROS-scavenging capacity than free Cur, which might arise from the enhanced solubility and chemical stability of the former.

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