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A Timosaponin B-II containing scalp care solution for improvement of scalp hydration, dandruff reduction, and hair loss prevention: A comparative study on healthy volunteers before and after application

文献类型： 外文期刊

作者： Xiao, Lei 1 ; Zhang, Xia 1 ; Chen, Zhiyi 3 ; Li, Bing 1 ; Li, Lin 1 ;

作者机构： 1.South China Univ Technol, Sch Food Sci & Engn, Guangdong Prov Key Lab Green Proc Nat Prod & Prod, Guangzhou 510640, Peoples R China

2.Infinitus China Co, Hong Kong, Peoples R China

3.Guangdong Acad Agr Sci, Sericultural & Agri Food Res Inst, Key Lab Funct Foods, Guangdong Key Lab Agr Prod Proc,Minist Agr & Rura, Guangzhou, Peoples R China

4.Dongguan Univ Technol, Sch Chem Engn & Energy Technol, Dongguan, Peoples R China

关键词： hair loss; redness reduction; dandruff; scalp hydration; Timosaponin B‐ II

期刊名称：JOURNAL OF COSMETIC DERMATOLOGY （ 影响因子：2.696； 五年影响因子：2.89 ）

ISSN： 1473-2130

年卷期： 2021 年 20 卷 3 期

页码：

收录情况： SCI

摘要： Background The plant species Anemarrhena asphodeloides has commonly been used for health and therapeutic purposes. Timosaponin B-II, which is present at a high concentration in A asphodeloides, was found to enhance the immune and anti-inflammatory responses of human bodies. Aims To evaluate benefits of a timosaponin B-II containing scalp care solution on hair loss prevention and scalp healthiness in multiple physiological and biological profiles. Methods Prior the study, 90 subjects applied scalp care solution base without timosaponin B-II for two weeks followed by application of the scalp care solution containing 0.5% timosaponin B-II for 28 days. The subject's hair follicle hydrocortisone level, hair fall number, hair luster level, dandruff level, sensation score, hydration level, lipid level, redness as well as the pH level of scalps were quantitatively assessed every 7 days. Results Multiple parameters on hair and scalp conditions were promoted by application of the timosaponin B-II containing scalp care solution. Compared to baseline values, significant improvements in hair luster, scalp hydration, hair fall number, and scalp redness level could be observed. Conclusion Timosaponin B-II promotes multiple physiological factors on hair and scalps. The scalp care solution containing A asphodeloides extracts may benefit the scalp healthiness and hair loss prevention.

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