An in-vitro study on a novel six-phage cocktail against multi-drug resistant-ESBL Shigella in aquatic environment
文献类型： 外文期刊
作者： Shahin, K. 1 ; Zhang, L. 1 ; Bao, H. 1 ; Hedayatkhah, A. 2 ; Soleimani-Delfan, A. 1 ; Komijani, M. 3 ; He, T. 1 ; Barazan 1 ;
作者机构： 1.Jiangsu Acad Agr Sci, Inst Food Safety & Nutr, Key Lab Food Qual & Safety Jiangsu Prov, State Key Lab Breeding Base, Nanjing, Peoples R China
2.Curtin Univ, Sch Pharm & Biomed Sci, Perth, WA, Australia
3.Arak Univ, Dept Biol, Fac Sci, Arak, Iran
4.Chinese Acad Sci, Suzhou Inst Nano Tech & Nanobion, Suzhou, Peoples R China
5.Univ Isfahan, Fac Biol Sci & Technol, Dept Cell & Mol Biol Microbiol, Esfahan, Iran
关键词： bacteriophage; bio‐ control; in‐ vitro; phage; phage cocktail; Shigella; water‐ borne
期刊名称：LETTERS IN APPLIED MICROBIOLOGY （ 影响因子：2.858； 五年影响因子：2.776 ）
ISSN： 0266-8254
年卷期： 2021 年 72 卷 3 期
页码：
收录情况： SCI
摘要： Shigella spp. are water-borne pathogens responsible for mild to severe cases bacilli dysentery all around the world known as Shigellosis. The progressively increasing of antibiotic resistance among Shigella calls for developing and establishing novel alternative therapeutic methods. The present study aimed to evaluate a novel phage cocktail of lytic phages against extended spectrum beta lactamase isolates of Shigella species in an aquatic environment. The phage cocktail containing six novel Shigella specific phages showed a broad host spectrum. The cocktail was very stable in aquatic environment. The cocktail resulted in about 99% decrease in the bacterial counts in the contaminated water by several species and strains of Shigella such as Shigella sonnei, Shigella flexneri and Shigella dysenteriae. Achieving such a high efficiency in this in-vitro study demonstrates a high potential for in-vivo and in-situ application of this phage cocktail as a bio-controlling agent against Shigella spp. contamination and infections.
- 相关文献
作者其他论文 更多>>
-
Creatine nitrate supplementation strengthens energy status and delays glycolysis of broiler muscle via inhibition of LKB1/AMPK pathway
作者：Duan, B. B.;Xu, J. W.;Xing, T.;Zhang, L.;Gao, F.;Li, J. L.
关键词：broiler; creatine nitrate; meat quality; energy status; glycolysis
-
Identification of a linear epitope in the capsid protein of goose astrovirus with monoclonal antibody
作者：Dai, G.;Huang, X.;Liu, Q.;Li, Y.;Zhang, L.;Han, K.;Yang, J.;Liu, Y.;Xue, F.;Zhao, D.;Dai, G.;Xue, F.;Zhao, D.;Zhao, D.;Dai, G.;Huang, X.;Liu, Q.;Li, Y.;Zhang, L.;Han, K.;Yang, J.;Liu, Y.;Zhao, D.
关键词：goose astrovirus; capsid protein; monoclonal antibody; epitope
-
Effects of dietary betaine supplementation subjected to heat stress on milk performances and physiology indices in dairy cow
作者：Zhang, L.;An, W. J.;Lian, H.;Zhou, G. B.;Han, Z. Y.;Ying, S. J.
关键词：Dairy cow;Heat stress;Betaine
-
Residue depletion of amoxicillin and its major metabolites in eggs
作者：Liu, Y. -N.;Xie, K. -Z.;Cui, L. -L.;Gao, Q.;Liu, J. -Y.;Wang, B.;Zhang, Y. -Y.;Zhang, G. -X.;Dai, G. -J.;Wang, J. -Y.;Liu, Y. -N.;Xie, K. -Z.;Gao, Q.;Liu, J. -Y.;Wang, B.;Zhang, Y. -Y.;Zhang, G. -X.;Dai, G. -J.;Wang, J. -Y.;Pang, M. -D.;Xie, X.;Wang, R.;Xie, X.
关键词：
-
Isolation and characterization of bacteriophages of Salmonella enterica serovar Pullorum
作者：Wang, R.
关键词：double-stranded DNA;plaque;HindIII: 81295-22-9;EcoRI;one-step growth kinetics
-
Photosynthetic characterization of three dominant plant species in the saline-alkaline soil of the Yellow River Delta, China
作者：Zhang, L.;Yan, K.;Shao, H.;Zhang, L.;Yan, K.;Shao, H.;Shao, H.
关键词：Cynanchum chinensis;Glycine soja;diurnal variation;Photosynthesis;Phragmites australis
-
Physical and chemical properties of gelatin from the skin of cultured Amur sturgeon (Acipenser schrenckii)
作者：Nikoo, M.;Ocen, D.;Yang, N.;Xu, X.;Benjakul, S.;Xu, B.;Zhang, L.
关键词：
