您好，欢迎访问中国水产科学研究院 机构知识库！
中国水产科学研究院机构知识库

全部

  • 全部
  • 标题
  • 学者
  • 机构
  • 关键词

Hepatopancreatic necrosis disease (HPND) in Chinese mitten crab Eriocheir sinensis tightly linked to low concentration of two insecticides

文献类型： 外文期刊

作者： Shen, Guoqing 1 ; Shui, Yan 2 ; Zhang, Xiao 1 ; Song, Kun 1 ; Wang, Yang 1 ; Xu, Zenghong 2 ; Shen, Huaishun 1 ;

作者机构： 1.Nanjing Agr Univ, Wuxi Fisheries Coll, Nanjing, Peoples R China

2.Minist Agr, Freshwater Fisheries Res Ctr, Key Lab Freshwater Fisheries & Germplasm Resource, Chinese Acad Fishery Sci, Wuxi, Jiangsu, Peoples R China

关键词： detoxifying enzyme; Eriocheir sinensis; histopathology; HPND; insecticide residues

期刊名称：AQUACULTURE RESEARCH （ 2020影响因子：2.082； 五年影响因子：2.415 ）

ISSN： 1355-557X

年卷期： 2021 年 52 卷 5 期

页码：

收录情况： SCI

摘要： To date, hepatopancreatic necrosis disease (HPND) in Eriocheir sinensis is causing huge financial losses to the aquaculture industry while the cause of HPND remains unclear. Our previous study has implied that HPND is probably relevant to the damages caused by insecticide residues. In this work, the comparative studies regarding histopathology and trends in immune-related/detoxifying enzymes activities of the crabs were performed between exposed to the low concentration of insecticides (i.e. beta-cypermethrin 8.52 x 10(-12 )g/L and trichlorfon 5 x 10(-5 )g/L) in a long-term (90-days) and suffered from HPND. The concentration was obtained by a median-lethal concentration (LC50) and a safe concentration (SC), and it was 10 times lower than the safe concentration in this experiment. This work's principal aim was to investigate the potential chronic effects of low concentrations of insecticides exposure on crabs and their relevance with HPND. As a result, crabs exposed to the low concentration of insecticides caused similar clinical symptoms and severity in hepatopancreas and other tissue damages like HPND. Meanwhile, catalase (CAT), superoxide dismutase (SOD), malondialdehyde (MDA), acid phosphatase (ACP), alkaline phosphatase (AKP), lysozyme (LZM) and carboxylesterase (CarE) enzymatic activity increased after exposure to the two insecticides and then decreased in the later stages, while the activity of glutathione S-transferase (GSTs) has barely changed. Results of enzymatic activity indicated that the two insecticides induced oxidative damage to the hepatopancreas of E. sinensis. These evidence indicated that the chronic damage caused by the low concentration of insecticides, which is considered insecticide residue, might be part of the causes of HPND in crabs. The present work may enhance our understanding of the pathogenesis of HPND and provide a theoretical basis for the management of intensive crab aquaculture.

  • 相关文献
作者其他论文 更多>>
置顶
购物车
反馈

© 京ICP备09089781号-29 主办单位：中国水产科学研究院

学术资源： 中国农业科学院 农业专业知识服务系统 农科联盟资源共建共享平台 中国农业科技文献与信息服务平台 中国农业期刊集成服务平台