Dissemination of the tet(X)-Variant Genes from Layer Farms to Manure-Receiving Soil and Corresponding Lettuce
文献类型： 外文期刊
作者： He, Tao 1 ; Wei, Rui-Cheng 1 ; Zhang, Lili 1 ; Gong, Lan 1 ; Zhu, Lei 1 ; Gu, Jili 1 ; Fu, Yu-Lin 2 ; Wang, Yang 2 ; Liu, De 1 ;
作者机构： 1.Jiangsu Acad Agr Sci, Inst Food Safety & Nutr, Jiangsu Key Lab Food Qual & Safety, State Key Lab Cultivat Base,Minist Sci & Technol, Nanjing 210014, Peoples R China
2.China Agr Univ, Coll Vet Med, Beijing Adv Innovat Ctr Food Nutr & Human Hlth, Beijing 100094, Peoples R China
期刊名称：ENVIRONMENTAL SCIENCE & TECHNOLOGY （ 影响因子：9.028； 五年影响因子：9.922 ）
ISSN： 0013-936X
年卷期： 2021 年 55 卷 3 期
页码：
收录情况： SCI
摘要： The occurrence of high-level tigecycline resistance tet(X) variant genes represents a new transferable resistance crisis to food safety and human health. Here, we investigated the abundance of tet(X)-variant genes [tet(X), tet(X1) to tet(X6)] in 33 samples collected from layer manures, manured/un-manured soils, and corresponding lettuce from three provinces in China. The results showed the occurrence of tet(X)/(X2), tet(X3), and tet(X4) in 24 samples. The detection rate of tet(X)/(X2) (23/24) is higher than that of tet(X3) (7/24) and tet(X4) (2/24), and tet(X)/tet(X2) and tet(X3) were found to be enriched and more abundant in most manured soil and several lettuce samples from manured soils than that from manure samples. Twenty six tigecycline-resistant bacteria were isolated, and tet(X)-variant genes were found to be disseminated not only by bacterial clone spreading but also via multidrug resistance plasmids. The total concentrations of tet(X)-variant genes showed significantly positive correlations (R = 0.683, p < 0.001) with ISCR2. Two veterinary tetracyclines (tetracycline and oxytetracycline) and other classes of antimicrobials (enrofloxacin, azithromycin, thiamphenicol, and florfenicol) showed significant correlations with the total concentrations of tet(X)-variant genes (R = 0.35-0.516, p < 0.05). The findings indicate the transmission of tet(X)-variant genes from layer manures to their receiving environmental soils and lettuce and highlight the contribution of veterinary antimicrobials to the spread of tet(X)-variant genes.
- 相关文献
作者其他论文 更多>>
-
Male-specific bacteriophages and their potential on combating the spreading of T4SS-bearing antimicrobial resistance plasmids
作者：Li, Jun;Ji, Xing;Wang, Ran;He, Tao;Garcia, Pilar
关键词：Antimicrobial resistance; type IV secretion systems; T4SS; conjugation; male-specific phages
-
Simulating the exploration of the optimal irrigation of spring wheat in drought areas based on SWAP model
作者：Jin, Jianxin;Ding, Yimin;Sun, Boyan;Li, Saiju;Guo, Zheng;Zhu, Lei;Jin, Jianxin;Ding, Yimin;Sun, Boyan;Li, Saiju;Guo, Zheng;Zhu, Lei;Jin, Jianxin
关键词：arid area; irrigation scheduling; spring wheat; SWAP; water productivity; zone aride; planification de l'irrigation; bl & eacute; de printemps; productivit & eacute; de l'eau
-
Evolution and transmission potential of iuc3-positive virulence plasmids in hypervirulent Klebsiella pneumoniae
作者：Wang, Jiayun;Wang, Heng;Wang, Jiayun;Ji, Xing;Li, Jun;Zhang, Lili;Wang, Ran;He, Tao;Garcia, Pilar
关键词：Klebsiella pneumoniae; HvKP; iucABCD; Genomic evolution; Conjugation; Plasmid fusion
-
Antimicrobial resistance and molecular epidemiology of Klebsiella pneumoniae isolated from bovine mastitis in seven provinces in China
作者：Wang, Jiayun;Wang, Heng;Wang, Jiayun;Li, Jun;Ji, Xing;Zhang, Lili;Wang, Ran;He, Tao
关键词：
Klebsiella pneumoniae ; Bovine; Mastitis; Genotyping; Antimicrobial resistance; Virulence -
The Virulence Factor LLO of Listeria monocytogenes Can Hamper Biofilm Formation and Indirectly Suppress Phage-Lytic Effect
作者：Liu, Banhong;Bai, Mei;Tu, Wuxiang;Bao, Hongduo;Wang, Ran;Zhang, Hui;Liu, Banhong;Tu, Wuxiang;Hu, Liangbing;Shen, Yanbin;Liu, Jingxin;Yang, Zhenquan;Dong, Qingli;Liu, Yangtai
关键词：
Listeria hemolysin ; biofilm; phage susceptibility; transcriptomics -
Characterization of LysBM1, a novel high-penetrating phage lysin targeting enterohemorrhagic Escherichia coli
作者：Liu, Haitao;Zhang, Shiqiang;Liu, Haitao;Sun, Quan;Zhang, Shiqiang;Sun, Lichang;Wang, Ran
关键词：Enterohemorrhagic Escherichia coli; phage; lysin; penetrating; food safety
-
Gut bacteriophages induce specific-reprogramming of macrophages to generate a protective innate immunity response to lipopolysaccharide exposure
作者：Hou, Xiang;Wang, Heye;Wang, Jing;Liu, Hui;Hu, Hao;Zhang, Lili;Hou, Xiang;Wang, Ran;Ding, Huiyan;Billington, Craig
关键词：Bacteriophage; innate immune memory; macrophage; IL-10; epigenetic mechanisms
