Strepolyketide D, a new SEK15-derived polyketide compound from salt-lake-derived Streptomyces sp. DBC5
文献类型： 外文期刊
作者： Bao, Xiao-Wei 1 ; Li, Yi-Xin 1 ; Chen, Xiao-Ming 3 ; Zhang, Zhi-Dong 2 ; Xu, Li-Juan 2 ; Liu, Xiao-Lu 1 ; Song, Su-Qin 2 ; Ma, Zhong-Jun 3 ;
作者机构： 1.Xinjiang Agr Univ, Sch Food Sci & Pharm, Urumqi 830052, Peoples R China
2.Xinjiang Acad Agr Sci, Inst Appl Microbiol, Xinjiang Key Lab Special Environm Microbiol, Urumqi 830091, Peoples R China
3.Zhejiang Univ, Ocean Coll, Inst Marine Biol, Zhoushan 316021, Peoples R China
4.Xinjiang Agr Univ, Coll Agron, Urumqi 830052, Peoples R China
关键词： Streptomyces sp; polyketide; antioxidant activity; strepolyketide D
期刊名称：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH （ 影响因子：1.61； 五年影响因子：1.591 ）
ISSN： 1028-6020
年卷期：
页码：
收录情况： SCI
摘要： A new SEK15-derived polyketide compound, strepolyketide D (1), was isolated from salt-lake-derived Streptomyces sp. DBC5, together with two known analogues (2-3). Their structures were elucidated based on spectroscopic analysis of IR, MS, 1 D and 2 D NMR. Compound 2 elicited moderate antioxidation with IC50 value of 39.26 mu g/ml. The results of the study revealed that salt-lake actinomycetes of Lake Dabancheng appear to have immense potential as a source of polyketide compounds.
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