Dietary supplementation of bilberry anthocyanin on growth performance, intestinal mucosal barrier and cecal microbes of chickens challenged with Salmonella Typhimurium
文献类型： 外文期刊
作者： Zhang, Sheng 1 ; Wang, Yibing 1 ; Ye, Jinling 1 ; Fan, Qiuli 1 ; Lin, Xiajing 1 ; Gou, Zhongyong 1 ; Jiang, Shouqun 1 ;
作者机构： 1.Guangdong Acad Agr Sci, Inst Anim Sci, State Key Lab Livestock & Poultry Breeding, Key Lab Anim Nutr & Feed Sci South China,Minist Ag, Guangzhou 510640, Guangdong, Peoples R China
关键词： Anthocyanin; Cecal microbe; Chicken; Intestinal mucosal barrier; Salmonella Typhimurium
期刊名称：JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY （ 影响因子：7.0； 五年影响因子：7.3 ）
ISSN： 1674-9782
年卷期： 2023 年 14 卷 1 期
页码：
收录情况： SCI
摘要： BackgroundAnthocyanins (AC) showed positive effects on improving the intestinal health and alleviating intestinal pathogen infections, therefore, an experiment was conducted to explore the protective effects of supplemented AC on Salmonella-infected chickens.MethodsA total of 240 hatchling chickens were randomly allocated to 4 treatments, each with 6 replicates. Birds were fed a basal diet supplemented with 0 (CON, and ST), 100 (ACL) and 400 (ACH) mg/kg of AC for d 60, and orally challenged with PBS (CON) or 10(9) CFU/bird (ST, ACL, ACH) Salmonella Typhimurium at d 14 and 16.Results(1) Compared with birds in ST, AC supplementation increased the body weight (BW) at d 18 and the average daily gain (ADG) from d 1 to 18 of the Salmonella-infected chickens (P < 0.05); (2) AC decreased the number of Salmonella cells in the liver and spleen, the contents of NO in plasma and inflammatory cytokines in ileal mucosa of Salmonella-infected chickens (P < 0.05); (3) Salmonella infection decreased the ileal villi height, villi height to crypt depth (V/C), and the expression of zonulaoccludins-1 (ZO-1), claudin-1, occludin, and mucin 2 (MUC2) in ileal mucosa. AC supplementation relieved these adverse effects, and decreased ileal crypt depth (P < 0.05); (4) In cecal microbiota of Salmonella-infected chickens, AC increased (P < 0.05) the alpha-diversity (Chao1, Pd, Shannon and Sobs indexes) and the relative abundance of Firmicutes, and decreased (P < 0.05) the relative abundance of Proteobacteria and Bacteroidota and the enrichment of drug antimicrobial resistance, infectious bacterial disease, and immune disease pathways.ConclusionsDietary AC protected chicken against Salmonella infection via inhibiting the Salmonella colonization in liver and spleen, suppressing secretion of inflammatory cytokines, up-regulating the expression of ileal barrier-related genes, and ameliorating the composition and function of cecal microbes. Under conditions here used, 100 mg/kg bilberry anthocyanin was recommended.
- 相关文献
作者其他论文 更多>>
-
Effects of L-Methionine and DL-Methionine on Growth Performance, Methionine-Metabolizing Enzyme Activities, Feather Traits, and Intestinal Morphology of Medium-Growing, Yellow-Feathered Chickens between 1 and 30 Days of Age
作者：Lin, Xiajing;Ruan, Dong;Lin, Zeling;Xiong, Taidi;Zhang, Sheng;Fan, Qiuli;Jiang, Zongyong;Jiang, Shouqun;Dong, Xiaoli;Deng, Yuanfan
关键词：methionine; feather trait; relative bioavailability; Met-metabolizing enzymes; broiler chickens
-
Betaine as an alternative feed additive to choline and its effect on performance, blood parameters, and egg quality in laying hens rations
作者：Zaki, Aisha;Zaghloul, Saad;El-Rayes, Talaat K.;Jiang, Shouqun;Saleh, Ahmed A.;Azzam, Mahmoud Mostafa;Ragni, Marco;Alagawany, Mahmoud
关键词：betaine; choline; performance; blood parameter; laying hen
-
Characteristics of glucolipid metabolism and oxidative stress in breeding pigeons (Columba livia) during lactation
作者：Peng, Jie;Huang, Weiying;Yang, Menglin;Gao, Hongyan;Lv, Yantao;Wang, Wei;Huang, Yanhua;Peng, Jie;Huang, Yanhua;Gou, Zhongyong;Wang, Ziying;Wang, Wei;Huang, Yanhua
关键词：breeding pigeon; glucolipid metabolism; lactation; oxidative stress
-
Optimal dietary energy and protein levels for breeding pigeons in the winter "2+3" lactation pattern
作者：Peng, Jie;Liang, Yayan;Zhang, Wei;Zhang, Yanlin;Yang, Menglin;Zheng, Shiqi;Lv, Yantao;Gao, Hongyan;Wang, Wei;Huang, Yanhua;Huang, Weiying;Peng, Jian;Gou, Zhongyong;Cheng, Chuanshang;Huang, Yanhua
关键词：breeding pigeon; reproductive performance; growth performance; oxidative stress; intestinal development
-
Evaluation of dietary metabolizable energy concentrations on meat quality and lipid metabolism-related gene expression in yellow-feathered chickens
作者：Cui, Xiaoyan;Cui, Xiaoyan;Gou, Zhongyong;Li, Long;Lin, Xiajing;Fan, Qiuli;Wang, Yibing;Jiang, Zongyong;Jiang, Shouqun;El-Senousey, Hebatallah Kasem
关键词：fiber density; intramuscular fat; metabolizable energy; volatile flavour; yellow-feathered broiler
-
Effects of granular feed on reproductive metabolism of breeding pigeons, intestinal development and microbiota of squab pigeons-A double-edged sword
作者：Zhang, Yanlin;Yang, Menglin;Zheng, Shiqi;Zhang, Wei;Huang, Weiying;Li, Ziying;Gao, Hongyan;Wang, Wei;Liang, Yayan;Huang, Yanhua;Peng, Jie;Zhang, Yanlin;Yang, Menglin;Zheng, Shiqi;Zhang, Wei;Huang, Weiying;Li, Ziying;Gao, Hongyan;Wang, Wei;Liang, Yayan;Huang, Yanhua;Peng, Jie;Gou, Zhongyong;Wang, Ziying
关键词：Granular feed; Breeding pigeon; Squab pigeon; Intestinal development; Microbiota
-
Transcriptome and proteome profile of jejunum in chickens challenged with Salmonella Typhimurium revealed the effects of dietary bilberry anthocyanin on immune function
作者：Zhang, Sheng;Wang, Qin;Ye, Jinling;Fan, Qiuli;Lin, Xiajing;Gou, Zhongyong;Wang, Yibing;Jiang, Shouqun;Azzam, Mahmoud M.
关键词：bilberry anthocyanin; Salmonella Typhimurium; immune status; transcriptome; proteome; yellow-feathered chicks
