Genome-Wide Association Study for Muscle Fat Content and Abdominal Fat Traits in Common Carp (Cyprinus carpio)
文献类型： 外文期刊
作者： Zheng, Xianhu 1 ; Kuang, Youyi 1 ; Lv, Weihua 1 ; Cao, Dingchen 1 ; Sun, Zhipeng 1 ; Sun, Xiaowen 1 ;
作者机构： 1.Chinese Acad Fishery Sci, Heilongjiang River Fisheries Res Inst, Natl & Local United Engn Lab Freshwater Fish Bree, Harbin, Heilongjiang, Peoples R China
2.Northeast Agr Univ, Coll Life Sci, Harbin, Heilongjiang, Peoples R China
期刊名称：PLOS ONE （ 影响因子：3.24； 五年影响因子：3.788 ）
ISSN： 1932-6203
年卷期： 2016 年 11 卷 12 期
页码：
收录情况： SCI
摘要： Muscle fat content is an important phenotypic trait in fish, as it affects the nutritional, technical and sensory qualities of flesh. To identify loci and candidate genes associated with muscle fat content and abdominal fat traits, we performed a genome-wide association study (GWAS) using the common carp 250 K SNP assay in a common carp F2 resource population. A total of 18 loci surpassing the genome-wide suggestive significance level were detected for 4 traits: fat content in dorsal muscle (MFdo), fat content in abdominal muscle (MFab), abdominal fat weight (AbFW), and AbFW as a percentage of eviscerated weight (AbFP). Among them, one SNP (carp089419) affecting both AbFW and AbFP reached the genome-wide significance level. Ten of those loci were harbored in or near known genes. Furthermore, relative expressions of 5 genes related to MFdo were compared using dorsal muscle samples with high and low phenotypic values. The results showed that 4 genes were differentially expressed between the high and low phenotypic groups. These genes are, therefore, prospective candidate genes for muscle fat content: ankyrin repeat domain 10a (ankrd10a), tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 (tanc2), and four jointed box 1 (fjx1) and choline kinase alpha (chka). These results offer valuable insights into the complex genetic basis of fat metabolism and deposition.
- 相关文献
作者其他论文 更多>>
-
Comprehensive Evaluation of Growth Performance, Hematological Parameters, Antioxidant Capacity, Innate Immunity, and Disease Resistance in Crucian Carp (Carassius auratus) Lacking Intermuscular Bones
作者：Zhao, Ran;Zhu, Jianqiang;Li, Shaowu;Sun, Zhipeng;Zhang, Tingting;Wang, Jing;Zheng, Xianhu;Kuang, Youyi;Wang, Di
关键词：Carassius auratus; a new strain lacking intermuscular bones; growth performance; iron overload; immune function
-
Establishment and Characteristics of the Spermatogonial Stem Cell Line from the Yellow River Carp (Cyprinus carpio haematopterus)
作者：Zhou, Huijie;Liu, Tianqi;Zhang, Tan;Sun, Zhipeng;Xu, Huan;Zhang, Tingting;Yin, Yashan;Li, Na;Yan, Ting;Kuang, Youyi;Zhou, Huijie;Liu, Tianqi;Zhang, Tan;Sun, Zhipeng;Xu, Huan;Zhang, Tingting;Yin, Yashan;Li, Na;Yan, Ting;Kuang, Youyi;Zhou, Huijie;Liu, Tianqi;Zhang, Tan;Sun, Zhipeng;Xu, Huan;Zhang, Tingting;Yin, Yashan;Li, Na;Yan, Ting;Kuang, Youyi;Zhou, Huijie;Yin, Yashan;Li, Na
关键词：
Cyprinus carpio haematopterus ; gonad stem cell culture; spermatogenesis; in vitro differentiation; transplantation -
Skin mucus proteomic provides insights into the alkaline tolerance of grass carp (Ctenopharyngodon idella)
作者：Li, Chenghao;Hu, Guo;Huang, Jing;Lu, Cuiyun;Zhang, Kexin;Zou, Yuting;Zhang, Limin;Zheng, Xianhu;Chang, Yumei;Shen, Yubang;Zou, Yuting
关键词：Ctenopharyngodon idella; Proteomics; Alkali-tolerant fish; Skin mucus
-
Transcriptome analysis reveals the candidate genes associated with skin color variation in Luciobarbus capito
作者：Geng, Longwu;Shang, Xinchi;Wei, Haijun;Tong, Guangxiang;Xu, Wei;Kuang, Youyi;Geng, Longwu;Shang, Xinchi;Wei, Haijun;Tong, Guangxiang;Xu, Wei;Kuang, Youyi
关键词：Transcriptomics; Pigmentation; Melanin; Carotenoids; Luciobarbus capito
-
Chromosome-level draft genome assembly of Hypomesus nipponensis reveals transposable element expansion reshaping the genome structure
作者：Zhu, Chenzhao;Tang, Fujiang;Zhu, Chenzhao;Kuang, Youyi;Li, Zhe;Tang, Fujiang
关键词：
Hypomesus nipponensis ; genome; evolutionary; gene family; repeat sequence -
Impact of Cold Stress on Hepatopancreas Transcriptomic and Metabolomic in Red Swamp Crayfish Procambarus clarkii
作者：Zhu, Xiaochen;Zhu, Xiaochen;Peng, Aidi;Zou, Yueying;Li, Yingdong;Wei, Hua;Zhao, Yingying;Zhu, Xiaochen;Zheng, Xianhu
关键词：
Procambarus clarkii ; cold stress; hepatopancreas; transcriptomic; metabolomic -
Multiple comparative analysis revealed genetic basis of residual feed intake trait in common carp (Cyprinus carpio L.)
作者：Xu, Yihua;Sun, Zhipeng;Liu, Tianqi;Na, Rongbin;Zhang, Kexin;Zheng, Xianhu;Lu, Cuiyun;Xu, Yihua;Zheng, Xianhu;Lu, Cuiyun
关键词：Cyprinus carpio L.; Residual feed intake; Histological analysis; Digestive enzyme activity; Comparative transcriptome
