文献类型： 外文期刊
作者： Zhou, Mingxu 1 ; Ding, Xueyan 2 ; Ma, Fang 1 ; Xu, Yue 1 ; Zhang, Jinqiu 1 ; Zhu, Guoqiang 2 ; Lu, Yu 1 ;
作者机构： 1.Jiangsu Acad Agr Sci, Inst Vet Immunol & Engn, 50 Zhongling St, Nanjing 210014, Jiangsu, Peoples R China
2.Yangzhou Univ, Coll Vet Med, Minist Educ China, Joint Int Res Lab Agr & Agriprod Safety, 12 East Wenhui Rd, Yangzhou 225009, Jiangsu, Peoples R China
3.Jiangsu Coinnovat Ctr Prevent & Control Important, 50 Zhongling St, Nanjing 210014, Jiangsu, Peoples R China
关键词： Long polar fimbriae; Escherichia coli; Virulence factor; Colonization
期刊名称：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY （ 影响因子：4.813； 五年影响因子：4.697 ）
ISSN： 0175-7598
年卷期： 2019 年 103 卷 18 期
页码：
收录情况： SCI
摘要： Long polar fimbria (LPF) is one of the few fimbrial adhesins of enterohemorrhagic Escherichia coli (E. coli) O157:H7 associated with colonization on host intestine, and both two types of LPF (including LPF1 and LPF2) play essential roles during the bacterial infection process. Though the fimbriae had been well studied in intestinal pathogenic E. coli strains, new evidences from our research revealed that it might be the key virulence for bovine mastitis pathogenic E. coli (MPEC) as well. This article summarizes the current knowledge on the LPF in E. coli, focusing on its genetic characteristics, prevalence, expression regulation, and adherence mechanism in different pathotypes of E. coli strains.
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