文献类型： 外文期刊

作者： Wan, Fanghao ¹ ; Yin, Chuanlin ³ ; Tang, Rui ⁴ ; Chen, Maohua ⁶ ; Wu, Qiang ¹ ; Huang, Cong ¹ ; Qian, Wanqiang ² ; Rota-S ¹ ;

作者机构： 1.Chinese Acad Agr Sci, Inst Plant Protect, State Key Lab Biol Plant Dis & Insect Pests, Beijing 100193, Peoples R China

2.Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Shenzhen 518120, Peoples R China

3.Zhejiang Univ, Key Lab Mol Biol Crop Pathogens & Insect Pests, Minist Agr, Inst Insect Sci,Coll Agr & Biotechnol, Hangzhou 310058, Zhejiang, Peoples R China

4.Chinese Acad Agr Sci, Inst Plant Protect, MARA CABI Joint Lab Biosafety, Beijing 100193, Peoples R China

5.Chinese Acad Sci, Inst Zool, State Key Lab Integrated Management Pest Insects, Beijing 100101, Peoples R China

6.Northwest A&F Univ, State Key Lab Crop Stress Biol Arid Areas, Key Lab Integrated Pest Management Crops Northwes, Minist Agr, Yangling 712100, Shaanxi, Peoples R China

7.Hunan Agr Univ, Coll Plant Protect, Changsha 410128, Hunan, Peoples R China

8.Fdn Edmund Mach, IASMA Res & Innovat Ctr, Dept Sustainable Agroecosyst & Bioresources, Via Mach 1, I-38010 San Michele All Adige, TN, Italy

9.Tech Ctr Anim Plant & Food Inspect & Quarantine, Shanghai Custom, Shanghai 200135, Peoples R China

10.Univ Kansas, Ecol & Evolutionary Biol, Lawrence, KS 66046 USA

11.INRA, Inst Ecol & Environm Sci Paris, F-78000 Versailles, France

12.INRA, Plantes & Syst Culture Horticole, 228 Route Aerodrome, F-84914 Avignon 09, France

13.Univ Pavia, Dept Biol & Biotechnol, I-27100 Pavia, Italy

14.Univ Trento, Ctr Agr Food Environm C3A, I-38010 San Michele All Adige, TN, Italy

15.Univ Edinburgh, Sch Biol Sci, Edinburgh Genom, Kings Bldg, Edinburgh EH9 3JT, Midlothian, Scotland

16.Univ Edinburgh, Sch Biol Sci, Inst Evolutionary Biol, Kings Bldg, Edinburgh EH9 3JT, Midlothian, Scotland

17.Czech Acad Sci, Inst Entomol, Biol Ctr, Branisovska 31, Ceske Budejovice 37005, Czech Republic

18.Univ South Bohemia, Fac Sci, Branisovska 760, Ceske Budejovice 37005, Czech Republic

19.Nanjing Agr Univ, Coll Plant Protect, Nanjing 210095, Jiangsu, Peoples R China

20.Xinjiang Acad Agr & Reclamat Sci, Inst Plant Protect, Shihezi 832000, Peoples R China

21.Qingdao Agr Univ, Coll Plant Hlth & Med, Qingdao 266109, Shandong, Peoples R China

22.Zhejiang Shuren Univ, Coll Biol & Environm Engn, Hangzhou 310015, Zhejiang, Peoples R China

23.Tarim Univ, Xinjiang Prod & Construct Corps Key Lab Integrate, Alar 843300, Peoples R China

期刊名称：NATURE COMMUNICATIONS （ 影响因子：14.919； 五年影响因子：15.805 ）

ISSN： 2041-1723

年卷期： 2019 年 10 卷

页码：

收录情况： SCI

摘要： The codling moth Cydia pomonella, a major invasive pest of pome fruit, has spread around the globe in the last half century. We generated a chromosome-level scaffold assembly including the Z chromosome and a portion of the W chromosome. This assembly reveals the duplication of an olfactory receptor gene (OR3), which we demonstrate enhances the ability of C. pomonella to exploit kairomones and pheromones in locating both host plants and mates. Genome-wide association studies contrasting insecticide-resistant and susceptible strains identify hundreds of single nucleotide polymorphisms (SNPs) potentially associated with insecticide resistance, including three SNPs found in the promoter of CYP6B2. RNAi knockdown of CYP6B2 increases C. pomonella sensitivity to two insecticides, deltamethrin and azinphos methyl. The high-quality genome assembly of C. pomonella informs the genetic basis of its invasiveness, suggesting the codling moth has distinctive capabilities and adaptive potential that may explain its worldwide expansion.